Lung volumes and forced ventilatory flows

Quanjer, P. H.; Tammeling, G. J.; Cotes, J. E.; Pedersen, Ole F.; Peslin, R; Jc, Yernault

doi:10.1183/09041950.005s1693

Cited by 4,612 publications

(1,122 citation statements)

References 222 publications

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“…Static lung volumes were available for 11 of the 17 CF patients. Data were expressed as a percentage of the predicted value [15]. The ratio between forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) was expressed as an absolute percentage and as a percentage of the predicted values.…”

Section: Lung Function Studiesmentioning

confidence: 99%

Cartilaginous airway wall dimensions and airway resistance in cystic fibrosis lungs

Tiddens¹,

Koopman²,

Lambert³

et al. 2000

Eur Respir J

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It is not clear how airway pathology relates to the severity of airflow obstruction and increased bronchial responsiveness in cystic fibrosis (CF) patients. The aim of this study was to measure the airway dimensions of CF patients and to estimate the importance of these dimensions to airway resistance using a computational model.Airway dimensions were measured in lungs obtained from CF patients who had undergone lung transplantation (n=12), lobectomy (n=1), or autopsy (n=4). These dimensions were compared to those of airways from lobectomy specimens from 72 patients with various degrees of chronic obstructive pulmonary disease (COPD). The airway dimensions of the CF and COPD patients were introduced into a computational model to study their effect on airway resistance.The inner wall and smooth muscle areas of peripheral CF airways were increased 3.3-and 4.3-fold respectively compared to those of COPD airways. The epithelium was 53% greater in height in peripheral CF airways. The sensitivity and maximal plateau resistance of the computed dose/response curves were substantially increased in the CF patients compared to COPD patients.The changes in airway dimensions of cystic fibrosis patients probably contribute to the severe airflow obstruction, and to increased bronchial responsiveness, in these patients. Eur Respir J 2000; 15: 735±742.

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Section: Lung Function Studiesmentioning

confidence: 99%

Cartilaginous airway wall dimensions and airway resistance in cystic fibrosis lungs

Tiddens¹,

Koopman²,

Lambert³

et al. 2000

Eur Respir J

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“…Allergic reactions are typically measured by skin tests, in which allergens are introduced percutaneously and flare or wheel sizes are measured (Zachariae, Jorgensen, Egekvist, & Bjerring, 2001). Decreased respiratory functioning may signal respiratory failure (Quanjer et al, 1993;Quanjer, Lebowitz, Gregg, Miller, & Pedersen, 1997;Rosenow, 2005) and poor symptom control. Respiratory system functioning is commonly assessed by expiratory volume (a measure of how much air a person exhales during a forced breath), peak expiratory volume (the maximal amount of flow expelled in a forced breath), and oxygen saturation (the percentage of oxygen the red cells carry).…”

Section: Introductionmentioning

confidence: 99%

Health benefits: Meta-analytically determining the impact of well-being on objective health outcomes

Howell

Kern

Lyubomirsky

2007

Health Psychology Review

515

334

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“…Pulmonary function was measured according to standardization recommendations (Quanjer, Tammeling, Cotes, Pedersen & Peslin, 1993) using a rolling-real spirometer (Mijnhardt Volugraph). The following indices of pulmonary function were assessed: (a) Forced Vital Capacity (FVC); (b) Forced Expiratory Volume in one second (FEV0; (c) Peak Expiratory Flow (PEF); (d) Forced Expiratory Flow at 50% of forced vital capacity (FEF 50%); and (e) the ratio of FEV~ to FVC (FEVffFVC).…”

Section: Assessmentmentioning

confidence: 99%

“…The following indices of pulmonary function were assessed: (a) Forced Vital Capacity (FVC); (b) Forced Expiratory Volume in one second (FEV0; (c) Peak Expiratory Flow (PEF); (d) Forced Expiratory Flow at 50% of forced vital capacity (FEF 50%); and (e) the ratio of FEV~ to FVC (FEVffFVC). With the exception of the FEVffFVC ratio, all indices were based on the percent predicted values derived from height, age and gender (Quanjer et al, 1993).…”

Section: Assessmentmentioning

confidence: 99%

“…Patients were instructed to remain medication-free for 24 hr prior to the pulmonary function testing in the outpatient Lung Function Laboratory of the University Hospital Leiden two weeks later. After they had been informed about the nature of the spirometry equipment, patients were asked to perform three forced vital capacity manoeuvres, from which the highest values were used in the analyses (Quanjer et al, 1993).…”

Section: Assessmentmentioning

confidence: 99%

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Pulmonary function in panic disorder: evidence against the dyspnea-fear theory

Spinhoven

Onstein

Sterk

1995

Behaviour Research and Therapy

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Summary--The present study addresses the hypothesis consistent with the dyspnea-fear theory of panic, that in a subgroup of panic patients a non-pathological pulmonary obstructive component may induce dyspnea, dyspneic fear and, ultimately, panic. In 38 patients who met DSM-III-R criteria for panic disorder, pulmonary function was assessed and various measurements for panic symptoms and concomitant psychopathology were collected. In comparison to patients with a high Forced Expiratory Flow at 50% (FEF 50%), low FEF 50% patients demonstrated significantly lower levels of Forced Expiratory Volume (first second) and Peak Expiratory Flow and significantly lower FEVJFVC ratios. None of the differences on psychological measurements for symptom severity between low and high FEF 50% patients proved to be significant. Moreover, FEF 50% scores and FEV#FVC ratios were not correlated to any of the measures for panic or associated psychopathology. It is concluded that the existence of a distinct subgroup of panic patients with signs of actual airway obstruction leading to uncontrollable dyspnea and fear of suffocation remains questionable.

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Lung volumes and forced ventilatory flows

Cited by 4,612 publications

References 222 publications

Cartilaginous airway wall dimensions and airway resistance in cystic fibrosis lungs

Cartilaginous airway wall dimensions and airway resistance in cystic fibrosis lungs

Health benefits: Meta-analytically determining the impact of well-being on objective health outcomes

Pulmonary function in panic disorder: evidence against the dyspnea-fear theory

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