Lupus erythematosus panniculitis in pregnancy

Abstract

A case of lupus erythematosus (LE) panniculitis in pregnancy without any lesions of discoid LE or systemic LE is being reported. There were no systemic symptoms. Her ANA, anti-dsDNA, anti-Ro/SSA, and anti-La/SSB antibodies were within normal limits. Diagnosis of lupus panniculitis was considered on clinical and histopathological grounds. The condition responded favorably to systemic steroid therapy.

Lupus erythematosus panniculitis in pregnancy and antimalarials

“…This is in reference to your case report “Lupus erythematosus panniculitis in pregnancy” published in the Indian Journal of Dermatology 2015;60:637. [ 1 ] I wholeheartedly appreciate the efforts of the authors in diagnosing and treating this case and also sharing their valuable experience. However, there are a few points in the manuscript that concern me and should have been taken care of.…”

Intravenous Immunoglobulin in the Management of Lupus Erythematosus Panniculitis

“…Lupus erythematosus panniculitis (LEP), also known as lupus profundus (LP), is a rare subtype of lupus erythematosus (LE) consisting of 1%-3% of patients with cutaneous lupus erythematosus (CLE) [1]. LEP is a chronic inflammatory process that mainly involves the deep dermis and subcutaneous tissues, usually presenting as deep indurated nodules or sharply demarcated plaques [2]. It can either present as the sole manifestation of the disease or in association with discoid lupus erythematosus (DLE) or systemic lupus erythematosus (SLE).…”

“…The most commonly involved areas include the lateral aspects of the arms and shoulders, buttocks, trunk, breast, face, and scalp [3]. Antimalarial medications are considered first-line therapy for most cases of LEP; meanwhile, systemic corticosteroids are saved for resistant lesions [2,4]. Intravenous immunoglobulin (IVIG) is derived from the blood of healthy blood donors and is made up of concentrated polyclonal immunoglobulin G (IgG).…”