Lupus vulgaris in a mother and child

Arora, Khushboo; Batra, Achla; Dhanta, Aditi; Hazarika, Neirita

doi:10.1136/bcr-2020-240591

Cited by 10 publications

(19 citation statements)

References 8 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Haematogenous or lymphatic dissemination accounts for the majority of cutaneous cases of TB. Among them, lupus vulgaris is a chronic, progressive, postprimary form of CTB, following a regional lymphatic or blood stream spread in individuals with moderate or high level of TB immunity [ 17 ▪ ]. Various clinical forms are observed: papular, nodular, with plaques, vegetative, ulcerative, mutilating, hypertrophic, atrophic, tumour-like type [ 17 ▪ ].…”

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

“…Among them, lupus vulgaris is a chronic, progressive, postprimary form of CTB, following a regional lymphatic or blood stream spread in individuals with moderate or high level of TB immunity [ 17 ▪ ]. Various clinical forms are observed: papular, nodular, with plaques, vegetative, ulcerative, mutilating, hypertrophic, atrophic, tumour-like type [ 17 ▪ ]. The buttocks and the extremities are usually involved in tropical and subtropical settings, face and neck in the West [ 17 ▪ ].…”

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

“…Various clinical forms are observed: papular, nodular, with plaques, vegetative, ulcerative, mutilating, hypertrophic, atrophic, tumour-like type [ 17 ▪ ]. The buttocks and the extremities are usually involved in tropical and subtropical settings, face and neck in the West [ 17 ▪ ]. Ramesh et al [ 10 ] recently described an Indian case series of lupus vulgaris affecting the pinna [ 10 ].…”

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

“…Ramesh et al [ 10 ] recently described an Indian case series of lupus vulgaris affecting the pinna [ 10 ]. Family history of lupus vulgaris has been described in high endemic areas [ 17 ▪ ]. Main differential diagnosis include leprosy, sarcoidosis, discoid lupus, leishmaniosis [ 17 ▪ ].…”

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

“…Family history of lupus vulgaris has been described in high endemic areas [ 17 ▪ ]. Main differential diagnosis include leprosy, sarcoidosis, discoid lupus, leishmaniosis [ 17 ▪ ]. Acute miliary skin TB and gummous TB are more commonly seen in patients with immunosuppressive disorders (i.e.…”

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

See 4 more Smart Citations

Mycobacterial skin infection

Giannotti

Gregori

Matteelli

et al. 2022

Current Opinion in Infectious Diseases

View full text Add to dashboard Cite

Purpose of review The aim of this article is to review the most recent evidences concerning mycobacterial skin infections, limiting the period of literature research to 2020--2021. Recent findings Mycobacterial skin infections include a heterogeneous group of cutaneous diseases. Cutaneous tuberculosis is usually the result of hematogenous dissemination or spread from underlying foci and it must be distinguished from tuberculids, resulting from the immunological reaction to Mycobacterium tuberculosis antigens. Leprosy prevalence was drastically reduced after introduction of multidrug therapy in the 1980 s, but cases are still reported due to underdiagnosis, and animal and environmental reservoirs. Recent advances concentrate in the diagnostic field. Specific guidelines for the treatment of nontuberculous mycobacteria skin infections are missing and surgical procedures may be required. Prognosis is better as compared to nontuberculous mycobacteria lung disease. Rapid laboratory-confirmed diagnosis of Buruli ulcer may be achieved by the IS2404 PCR. Among new drugs, telacebec is promising in terms of potency, shorter duration and tolerability in animal studies. A clinical trial in humans is planned. Summary Mycobacterial cutaneous lesions are nonpathognomonic and clinical suspicion must be confirmed by culture or molecular detection. Long-course multidrug treatment is required based on susceptibility tests. Surgical intervention may also be required. Rehabilitation and psychosocial support reduce long-term physical and mental consequences mostly in Buruli ulcer and leprosy.

show abstract

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

Section: Mycobacterial Skin Infectionsmentioning

confidence: 99%

See 3 more Smart Citations

Mycobacterial skin infection

Giannotti

Gregori

Matteelli

et al. 2022

Current Opinion in Infectious Diseases

View full text Add to dashboard Cite

show abstract

Giant facial lupus vulgaris

Bendaoud,

Faras,

Boujguenna

et al. 2024

Oxford Medical Case Reports

View full text Add to dashboard Cite

Lupus vulgaris: a narrative review

Couppoussamy,

Shanmugam,

Devanda

et al. 2023

Int J Dermatology

View full text Add to dashboard Cite

Lupus vulgaris (LV) is a type of paucibacillary cutaneous tuberculosis that can occur due to inoculation, lymphatic, or hematogenous route. It occurs in a previously sensitized individual with high immunity to tuberculosis. LV can have different morphology of presentation, which can lead to difficulty in diagnosis. The Tuberculin test is strongly positive. Histopathology will show epithelioid granulomas in the superficial dermis and acid‐fast bacilli rarely demonstrable within the granulomas. Dermoscopy will show focused linear vessels on a yellow to orange background. Culture is the gold standard for diagnosis, but its positivity rate is low. Mycobacterium tuberculosis bacilli can be detected using polymerase chain reaction from the lesions. Histopathology, tuberculin test, dermoscopy, molecular test, and culture would help diagnose LV. This review discusses the introduction, pathogenesis, clinical features, differential diagnosis, investigations, complications, and treatment of lupus vulgaris in detail. This review can help the dermatologist understand the condition better with appropriate diagnosis and therapy.

show abstract

Lupus vulgaris in a mother and child

Cited by 10 publications

References 8 publications

Mycobacterial skin infection

Mycobacterial skin infection

Giant facial lupus vulgaris

Lupus vulgaris: a narrative review

Contact Info

Product

Resources

About