Luteal support of pregnancy in red deer (Cervus elaphus): effect of cloprostenol, ovariectomy and lutectomy on the viability of the post-implantation embryo

Asher, G. W.; Fisher, M. W.; Berg, D.K.; Waldrup, Kenneth A.; Pearse, A. J.

doi:10.1016/0378-4320(95)01447-0

Cited by 12 publications

(4 citation statements)

References 22 publications

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“…Once pregnancy was confirmed, abortion was induced using two doses of prostaglandin F 2a 6 h apart (25 mg, i.m. ; Lutalyse; Pharmacia & Upjohn, Kalamazoo, MI) [30,31].…”

Section: Pregnancy and Ovarian Measurementsmentioning

confidence: 99%

Effects of Gonadotropin-Releasing Hormone Immunization on Reproductive Function and Behavior in Captive Female Rocky Mountain Elk (Cervus elaphus nelsoni)1

Powers¹,

Baker²,

Davis³

et al. 2011

Biology of Reproduction

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Fertility control is a potential method for managing overabundant wildlife populations; however, current technology is limited by duration of treatment efficacy and unacceptable side effects. The objective of this study was to determine the efficacy of a single immunization with gonadotropin-releasing hormone (GnRH) vaccine to suppress reproductive function in pregnant female elk and to evaluate potential behavioral and pathological side effects of treatment. Eighteen captive adult female elk were randomly allocated to one of two experimental groups. Ten females were administered a conjugated and adjuvanted GnRH vaccine intramuscularly, and eight elk received an adjuvant sham vaccine without conjugated GnRH. We compared success of existing pregnancy, neonatal survival, subsequent fertility, reproductive behavior rates, and side effects of treatment between January 2006 and January 2010. The GnRH vaccination did not affect existing pregnancy or calf survival during the year that it was applied; however, it reduced the proportion of pregnant females for 3 yr. Male precopulatory behavior rates exhibited toward GnRH-vaccinated females tended to be greater than those directed at sham-vaccinated females during the second half of the breeding season, when GnRH vaccinates continued to be proceptive. Strong immune and inflammatory responses, including robust GnRH antibody concentrations in GnRH vaccinates, and sterile pyogranulomatous injection site abscesses in both groups, were consistent with vaccination. In conclusion, this GnRH vaccine resulted in prolonged, albeit reversible, impairment of fertility, and is associated with extended reproductive behaviors and partial suppression of hypothalamic-pituitary-gonadal axis function in captive female elk.

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“…Once pregnancy was confirmed, abortion was induced using two doses of prostaglandin F 2a 6 h apart (25 mg, i.m. ; Lutalyse; Pharmacia & Upjohn, Kalamazoo, MI) [30,31].…”

Section: Pregnancy and Ovarian Measurementsmentioning

confidence: 99%

Effects of Gonadotropin-Releasing Hormone Immunization on Reproductive Function and Behavior in Captive Female Rocky Mountain Elk (Cervus elaphus nelsoni)1

Powers¹,

Baker²,

Davis³

et al. 2011

Biology of Reproduction

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“…The almost complete suspension in spermatogenesis, during the non-rutting season (February-April), is further proof of such synchronization process [11]. Progesterone (P4) secreted by corpora lutea is necessary for the maintenance of pregnancy [12,13], while the contribution of placental progesterone is still to be assessed. P4 blood concentrations remain high ( 4 ng/mL) for the duration of gestation, and start decreasing one to two days before parturition in order to reach baseline levels after delivery [4,14].…”

Section: Introductionmentioning

confidence: 99%

Progesterone and Cortisol Levels in Blood and Hair of Wild Pregnant Red Deer (Cervus Elaphus) Hinds

Ventrella

Elmi

Bertocchi

et al. 2020

Animals

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The red deer (Cervus elaphus L., 1758) is one of the largest deer species in the world. Females are seasonal polyestrous, with negative photoperiod: the increase of the night peak of melatonin determines the secretion of GnRH and, therefore, LH and FSH. To date there is little information regarding the hormonal control during pregnancy for this species; this could be due to the difficulty of sampling wild subjects, while farmed animals’ hormonal concentrations may not reflect the physiology of the animal in a natural state. In this study we evaluated the concentration of cortisol and progesterone, extracted from blood and hair, on 10 wild and pregnant red deer females. Belonging to the population of the Bolognese Apennines (Italy), the hinds were sampled in the January–March 2018 period, according to the regional selective hunting plan. Plasma progesterone (P4) ranged from a minimum of 1.9 to a maximum of 7.48 ng/mL; while hair P4 concentrations varied from 41.68 to 153.57 pg/mg. The plasma and hair cortisol ranges are respectively 0.4–2.97 ng/mL and 0.03–0.55 pg/mg; the only significant correlation was found between hair concentration of P4 and the date of death. The results of this preliminary study represent a small step towards a better knowledge of this species’ physiology during pregnancy.

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“…A higher level of progesterone has to be expected in pregnant hinds when compared to non-pregnant animals (Korzekwa et al, 2016). Hormone progesterone secreted by corpora lutea is necessary for the maintenance of pregnancy (Asher et al, 1996). Female cervids are polyoestrous, and non-pregnant animals can exhibit continuously repeated oestrous cycles or, more commonly, alternating periods of oestrous cyclicity and anoestrus (Asher, 2010).…”

Section: Hormone Analysismentioning

confidence: 99%

Non-Invasive Measurement of Progesterone and Cortisol Metabolites in the Faeces of Captive Female Rusa unicolor at Zoo Negara, Malaysia and Its Reproductive and Stress Behaviour

Hamid¹,

Nadzir²,

Omar³

et al. 2022

JST

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Sambar deer are listed as vulnerable and are bred in captivity under governmental management. The success of captive breeding programs varies, and the underlying causes are unclear. The advantage of using non-invasive faecal samples to obtain hormonal profiles without the animal being sedated or restrained has not been tested in sambar deer. This experiment was aimed to study the reproductive and stress behaviours of sambar deer and to measure the levels of reproductive and stress hormones in captive female sambar deer via a non-invasive procedure using faeces samples. Data on reproductive and stress behaviour were collected from six sambar deer for six months. Behaviours were recorded by instantaneous sampling method using direct observation. The reproductive and stress hormones in faecal samples were analysed using ELISA procedures. There are differences in frequency of certain reproductive behaviours recorded within different sessions of data collections while stress behaviour was in the low count and no huge difference in frequency between different sessions. Progesterone metabolites showed some trend of high concentrations in July and started to drop at the end of July till the end of December with constantly negative concentrations. Sambar deer in Zoo Negara can be considered not in stress due to low reading of cortisol concentration even though there was a presence of visitors. In future, it is important to make sure the faecal samples for hormonal analysis are collected daily to look for the pattern of the oestrus cycle in sambar deer.

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Luteal support of pregnancy in red deer (Cervus elaphus): effect of cloprostenol, ovariectomy and lutectomy on the viability of the post-implantation embryo

Cited by 12 publications

References 22 publications

Effects of Gonadotropin-Releasing Hormone Immunization on Reproductive Function and Behavior in Captive Female Rocky Mountain Elk (Cervus elaphus nelsoni)1

Effects of Gonadotropin-Releasing Hormone Immunization on Reproductive Function and Behavior in Captive Female Rocky Mountain Elk (Cervus elaphus nelsoni)1

Progesterone and Cortisol Levels in Blood and Hair of Wild Pregnant Red Deer (Cervus Elaphus) Hinds

Non-Invasive Measurement of Progesterone and Cortisol Metabolites in the Faeces of Captive Female Rusa unicolor at Zoo Negara, Malaysia and Its Reproductive and Stress Behaviour

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