Luteolysis in the ewe: a study using a radioimmunoassay for prostaglandin F

Jc, Cerini; Cain,; Wa, Chamley; Cumming, I. A.; Findlay, J. K.; Goding,

doi:10.1530/jrf.0.0320326

Cited by 2 publications

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“…Maternal recognition of pregnancy in sheep and cattle (d 13 and 16, respectively), has also been well-studied. As in pigs, luteolysis is caused by PGF 2a release from the uterus (Chamley et al, 1972;Cerini et al, 1973). The role of oxytocin and oxytocin receptors in this process has been clearly established.…”

Section: Embryonic Mortalitymentioning

confidence: 99%

The influence of uterine function on embryonic and fetal survival

Vallet

Leymaster

Christenson

2002

Journal of Animal Science

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The secretion rate of growth factors and the delivery rate of nutrients by the uterus to the conceptus affects the growth rate, development, and survival of the conceptus. For most growth factors and nutrients, passage into the uterus is not simply controlled by diffusion. Many growth factors are products of uterine tissue. Transport of some nutrients is aided by specific transporter molecules on the uterine endometrial epithelial cell, whereas others (e.g., retinol, iron, and folate) are incorporated into uterine-secreted proteins (e.g., retinol binding protein, uteroferrin, and folate binding protein). The rate of production of these proteins during pregnancy profoundly affects pregnancy outcome. Uterine gland knockout experiments in sheep demonstrate that pregnancy fails in the absence of uterine glands, the source of many uterinesecreted proteins. In pigs, both global and specific effects of uterine products on aspects of conceptus development can influence litter size. The provision of growth factors and nutrients by the uterus plays a role in en

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Section: Embryonic Mortalitymentioning

confidence: 99%