We produce a family of new, non-arithmetic lattices in PU(2, 1). All previously known examples were commensurable with lattices constructed by Picard, Mostow, and DeligneMostow, and fell into 9 commensurability classes. Our groups produce 5 new distinct commensurability classes. Most of the techniques are completely general, and provide efficient geometric and computational tools for constructing fundamental domains for discrete groups acting on the complex hyperbolic plane.