Lycopene Inhibits Helicobacter Pylori-Induced Hyperproliferation through Suppression of β-Catenin Signaling in Gastric Epithelial Cells

Park, Bohye; Lim, Joo Weon; Kim, Hye Young

doi:10.1016/j.freeradbiomed.2014.10.351

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is reported that lycopene intake (about 100 mg/kg) in rats could significantly decrease high malondialdehyde level and myeloperoxidase activity and increase the activity of antioxidant enzymes (with the exception of catalase) in tissue (Boyacioglu et al , 2016) (Table I). Although lycopene can inhibit Helicobacter pylori ( H. pylori ) infection which is a risk factor for gastric cancer, its hyperproliferation through suppression of beta-catenin signaling was assigned of gastric epithelial cells (Park et al , 2014).…”

Section: Lycopene and Human Healthmentioning

confidence: 99%

The role of lycopene in human health as a natural colorant

Nedamani¹,

Nedamani

Salimi

2019

NFS

View full text Add to dashboard Cite

Purpose Human health is strongly affected by diet. By the increased use of food industries products, public knowledge about health factors and side effects of chemical additives, the concepts of human health founded an important aspect during past years, and application of natural-based ingredients such as coloring, flavoring, texturizing and anti-oxidative agents was increased. Design/methodology/approach The aim of the present paper is to review the published scientific research studies about lycopene health benefits in different human disease or disorders and bold the necessity of study the health effects of lycopene after its formulation in food industrial products. About 190 papers were searched in Google Scholar, PubMed, Web of Science databases and 72 relevant papers were used. It was found that in medical studies, the lycopene oleoresin or powder is used directly to the subjects. However, it is necessary to study the effectiveness of lycopene in diet food products. Findings According to the literature, it has beneficial effects on cancers, glands, reproductive system, bone, gastric system, liver and fat reduction in the body. Also, it was concluded from the literature that lycopene oxidative cleavages make also its chemo protective effects which is a lost key element to study different food processing on lycopene products or its isomers in final food products and on human health. Originality/value Many ingredients in food formulations are substituted by natural products. Lycopene is a colorant but also, according to the literature, has a strong antioxidative and anti-inflammatory effect to reduce the risk of most important human disease and disorders. Future research in food science can emphasize the effect of different unit operations or formulations on lycopene effects on human health.

show abstract

Section: Lycopene and Human Healthmentioning

confidence: 99%