Lyme disease—another transfusion risk?

Aoki, S. K.; Holland, P. V.

doi:10.1046/j.1537-2995.1989.29789369687.x

Cited by 25 publications

(5 citation statements)

References 49 publications

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“…The agent was cultured from the deer tick, Ixodes dammini in 1982 and from patients with Lyme disease in 1983. 64 It causes a classic localised skin rash, erythema chronicum migrans, and patients untreated or unrecognised go on to develop a protean illness with arthritic, neurologic or cardiac manifestations. Unlike Treponema pal/idum, the spirochaete of Lyme disease survives storage in blood components quite well.…”

Section: Lyme Diseasementioning

confidence: 99%

Transfusion Transmitted Infection: Viral and Exotic Diseases

1993

Anaesth Intensive Care

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Viral and other exotic diseases may be transmitted by blood transfusion. These infections include human immunodeficiency virus (HlV), hepatitis viruses (A, B, C, D and E), syphilis, malaria, retrovirus HTLV-I, and cytomegalovirus. Other more exotic diseases which may be transmitted by transfusion of blood or blood components include Chagas' disease (Trypanosomiasis cruzi), Lyme disease (Borrelia bUrgdorferi), and lakob-Creutifeldt disease. Screening procedures currently used in Australian blood banks minimise transfusion-transmitted infection. The risk of acquiring any infection in this manner may be less than 0.1%.

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Section: Lyme Diseasementioning

confidence: 99%

Transfusion Transmitted Infection: Viral and Exotic Diseases

1993

Anaesth Intensive Care

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“…Kan ve kan bileşenleri transfüzyonu sonrasında B. Burgdorferi (70) , Y. enterocolitica (71,72) ve Salmonella türlerinin (73) , nadiren enfeksiyona neden olduğu bilinmektedir.…”

Section: Diğer Bakterilerunclassified

Infectious Agents Transmitted by Blood and Blood Component and Impacts of Nükleik Asit Amplifikasyon Test (NAT)

Savasci¹,

Avcı²

2016

IKSST

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ÖZ Kan ve kan¸bileşenleri ile bulaşan enfeksiyonlar, özellikle viral hepatit virüsleri ve insan immün yetmezlik virüsü¸ (HIV), ABSTRACT Especially viral hepatitis viruses and human immunodeficiency virus (HIV) which are transmitted by the transfusion of blood and blood products have been an important public health problem for a long time in the world. Transfusion of blood and blood products is an ideal, easiest and a simplest route for transmission of infectious diseases. It is known that many infectious agents, either bacterial, viral, parasitic and fungal agents may be transmitted by the transfusion of blood and blood products. Nucleic Asit Amplification Test (NAT) provides additional layer of safety to the blood supply because it allows the detection of infectious agents during their incubation periods. Keywords: blood, blood center, infection, nucleic acid amplification test GİRİŞKan ve kan bileşenleri hayati tehlikeye neden olan birçok hastalık ve travmalarda tedavi amaçlı kullanı-lan bileşenlerdir. Kan ve kan bileşenlerinin tek kaynağının insan olması nedeniyle temini çok zor ve maliyet açısından oldukça pahalı bileşenlerdir. Kan naklinin güvenli bir şekilde yapılması, nakil sonrası ortaya çıkabilecek enfeksiyonların önlenebilmesine bağlıdır. Dünyada her yıl milyonlarca ünite kan ve kan bileşenleri kullanılmakta ve alıcıların bir kısmın-da transfüzyona bağlı enfeksiyonlar ortaya çıkmakta-dır. Kan ve kan bileşenlerinin kullanımı aracılığıyla bağışçıda mevcut enfeksiyon etkeninin alıcıya aktarılması tamamıyla engellenememektedir. Bu nedenle amaç, bu tip bulaşma risklerini "kabul edilebilecek kadar düşük" düzeylere indirgemek olmuştur (1) .Kan ve kan bileşenleri ile birçok enfeksiyon etkeni bulaşabilmektedir. Tarama testlerine rağmen neden enfeksiyon bulaşır sorusuna yanıt şu şekilde verilebilir. Transfüzyonla bulaşan enfeksiyon etkenlerinin dolaşımda uzun süre kalmaları, uzun inkübasyon süreleri, mutant suşların varlığı, asemptomatik klinikle seyretmeleri, kan ve kan bileşenlerinde stabilitelerini korumaları önemli özellikleridir. Enfeksiyon etkenleri arasında virüsler en önemli grubu oluştur-maktadır. En fazla sorun olan virüsler; hepatit B

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“…Lyme disease is now the most common tick-transmitted disease in the United States; more than 1,500 cases are reported each year. The possibility of BoweIth brrrgdo&ri transmission by transfusion has become a concern, because (1) the incidence of Lyme disease is rapidly increasing, (2) bacteremia occurs in the early stages of the disease, and (3) the organism is viable in whole blood under blood bank conditions up to 60 days [133,134]. In every documented case of Lyme borreliosis, clinical symptoms were present and potential blood donors with infection would have been recognized.…”

Section: Bacteriamentioning

confidence: 99%

Blood-borne Infections Associated with Transfusion

Ulrich

Vyas

1992

J Intensive Care Med

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Ulrich PP, Vyas GN. Blood-borne infections associated with transfusion. J Intensive Care bled 1992;7:67-83.The epidemic of acquired immunodeficiency syndrome (AIDS) and the realization that transmission of human immunodeficiency virus is caused by homologous blood transfusion have changed the way physicians and their patients view the safety of hemotherapy. Considering that nearly four million patients receive the lifesaving benefits of blood transfusions every year in the United States, w e need to recognize and reduce the inherent biologicd complications of this therapy. Currently, a major concern is the transmission of blood-borne infectious agents and the establishment of persistent infection in transfusion recipients, which is apparently facilitated by suppression of the recipient's hematopoietic and immune systems. Education of blood donors, patients, and attending physicians regarding infectious complications of transfusion is essential and remains the most effective procedure for making rational decisions. Before giving blood transfusions, astute physicians should calculate a risWbenefit ratio and communicate it to the patient or family. Potential recipients of transfusions can be assured that the blood supply is safer now than at any time in the past, although there is still a very small risk for the transmission of infectious agents that cause chronic diseases, such as hepatitis, AIDS, neuropathies, and leukemias. It is essential that everyone understands that the goal of a zero-risk blood supply is not attainable. Recent developments in molecular biology and biotechnology, however, provide opportunities for further reduction of infectious complications of blood transfusions.

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Lyme disease—another transfusion risk?

Cited by 25 publications

References 49 publications

Transfusion Transmitted Infection: Viral and Exotic Diseases

Transfusion Transmitted Infection: Viral and Exotic Diseases

Infectious Agents Transmitted by Blood and Blood Component and Impacts of Nükleik Asit Amplifikasyon Test (NAT)

Blood-borne Infections Associated with Transfusion

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