Lyme optic neuritis

Blanc, F.; Ballonzoli, Laurent; Marcel, Christophe; Martino, S. De; Jaulhac, B.; Seze, J. de

doi:10.1016/j.jns.2010.05.009

Cited by 46 publications

(25 citation statements)

References 22 publications

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“…Notably, the optic nerve is rarely if ever affected; lower cranial nerve involvement is limited to isolated case reports only. [53][54][55] Mononeuropathy Some patients develop a typical mononeuropathy or mononeuropathy multiplex: focal involvement of one or several individual peripheral nerves. Occasionally, this can involve the brachial or lumbosacral plexus, the complex structures in which the nerves to the limbs form from the originating spinal nerve roots.…”

Section: Cranial Neuritismentioning

confidence: 99%

Nervous System Lyme Disease

Halperin

2015

Clinics in Laboratory Medicine

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Section: Cranial Neuritismentioning

confidence: 99%

Nervous System Lyme Disease

Halperin

2015

Clinics in Laboratory Medicine

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“…For example, although relatively rare, we recently report typical cases of ON secondary to Lyme disease. 6 Cerebrospinal analysis frequently shows lymphocytic meningitis and a high intrathecal index for Borrelia, which is a very highly specific but only 70% sensitive test for ''neurolyme.'' 7 Recently, we also observed in our department an increased number of cases with ON secondary to syphilis or human immunodeficiency virus (HIV), but the majority of these cases were a neuroretinitis syndrome rather than typical ON without signs of cerebral inflammation on MRI or latency delay on visual evoked potentials (unpublished data).…”

Section: Optic Neuritis Due To Infectionmentioning

confidence: 99%

Inflammatory Optic Neuritis: From Multiple Sclerosis to Neuromyelitis Optica

Seze

2013

Neuro-Ophthalmology

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Inflammatory optic neuritis represents a frequent clinical situation in neurology and ophthalmology. In those parts of the world where multiple sclerosis is common, it is the condition most discussed as the cause of optic neuritis. However, the risk for conversion from optic neuritis to multiple sclerosis is evaluated at only around 50% after 15 years of follow-up. The risk is higher in cases in whom abnormalities typical of multiple sclerosis are found on magnetic resonance imaging of the brain and oligoclonal bands found on cerebrospinal fluid protein electrophoresis with no corresponding bands in serum. When these investigations are normal, optic neuritis is usually considered as ''idiopathic'' with a suspected viral aetiology, but in some cases, a systemic disease such as sarcoidosis, systemic lupus erythematosis, or Sjö gren syndrome may be diagnosed. In rare cases, either recurrent optic neuritis or myelitis may occur without any evidence for multiple sclerosis. In the first case, it corresponds to a recently characterised disorder referred to as chronic relapsing inflammatory optic neuropathy and in the second case to a recently better identified entity, neuromyelitis optica. In the present paper, the differential diagnosis of inflammatory optic neuritis is presented from multiple sclerosis to infectious optic neuritis, systemic disease, and neuromyelitis optica.

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“…In the majority of these cases a positive intratechal anti-Borrelia antibody index was found, accompanied in less than half of the cases by CSF pleyocytosis. The antibiotic treatment led to the amelioration of visual symptoms, even when a delay of a few months existed between the clinical onset and the initiation of treatment (22,23). Lyme disease as a cause of optic neuropathy may be underdiagnosed.…”

Section: Acute Optic Neuropathymentioning

confidence: 99%