Lymphadenectomy for Colorectal Cancer: Experience of the Brazzaville Teaching Hospital

Ossibi, Pierlesky Elion; Madzele, Murielle Etiennette Julie Note; Latou, Noé Hensnel Motoula; Miabaou, Didace Massamba; Avala, Prude Pertinie; Mimiesse-Monamou, Jile Florient; Mongo-Onkouo, Arnaud; Ngami, Rody Stéphane; Mouamba, Fabien Gael; Ndounga, Eliane; Liboko, Alexis Fortuné Bolenga; Moyikoua, Régis; Mabonzo, Freznel Ngoma; Ahoui, Apendi Philestine Clausina; Otiobanda, Gilbert Fabrice; Ibara, Blaise Irénée Atipo

doi:10.4236/ss.2022.133011

Cited by 2 publications

(1 citation statement)

References 41 publications

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“…In Congo, the activity of laparoscopic surgery in digestive surgery began in 2009 with the fairly regular practice of cholecystectomy for vesicular stones [10]. With regard to AA in its uncomplicated form, which accounts for 21.1% of abdominal surgical emergencies admitted to the University Hospital of Brazzaville, a recent study reports its surgical treatment [11]. It was reported that of all patients operated in this setting, a small proportion had undergone a laparoscopic approach.…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic Appendectomies at Brazzaville University Hospital

Madzele,

Ossibi,

Monwongui

et al. 2024

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Introduction: Acute appendicitis represents an urgent surgical condition, requiring the removal of the vermiform appendix. Laparoscopy is the standard surgical approach. This study aimed to outline the epidemiological, clinical, therapeutic, and outcome characteristics of patients undergoing laparoscopic surgery for acute appendicitis. Patients and Methods: A descriptive, retrospective analysis was carried out in the Emergency and Digestive Surgery departments of the University Hospital Center of Brazzaville, spanning two years from January 1, 2021, to December 31, 2022. The study included all patients who underwent laparoscopic surgery for non-complicated acute appendicitis. Results: The study included 12 cases of non-complicated acute appendicitis treated with urgent laparoscopy. The mean age of the patients was 37 ± 8.9 years, with a sex ratio of 0.7. The predominant symptom leading to consultation was pain in the right iliac fossa, with an average time to consultation of 6.4 ± 5.7 hours. Patient histories included diabetes in one case, obesity in two cases, and one case of prior abdominoplasty. During surgery, a phlegmonous appendix was observed in nine patients. The average duration of hospital stay was 3.6 ± 1.3 days, with all patients experiencing uncomplicated recoveries. Conclusion: The practice of emergency laparoscopic appendectomy is still relatively infrequent in our setting and presents an ongoing challenge.

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Section: Introductionmentioning

confidence: 99%

Laparoscopic Appendectomies at Brazzaville University Hospital

Madzele,

Ossibi,

Monwongui

et al. 2024

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Suppressed oncogenic molecules involved in the treatment of colorectal cancer by fecal microbiota transplantation

Han,

Zhang,

Zeng

et al. 2024

Front. Microbiol.

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Dysbiosis of the intestinal microbiota is prevalent among patients with colorectal cancer (CRC). This study aims to explore the anticancer roles of the fecal microbiota in inhibiting the progression of colorectal cancer and possible mechanisms. The intestinal microbial dysbiosis in CRC mice was significantly ameliorated by fecal microbiota transplantation (FMT), as indicated by the restored ACE index and Shannon index. The diameter and number of cancerous foci were significantly decreased in CRC mice treated with FMT, along with the restoration of the intestinal mucosal structure and the lessening of the gland arrangement disorder. Key factors in oxidative stress (TXN1, TXNRD1, and HIF-1α); cell cycle regulators (IGF-1, BIRC5, CDK8, HDAC2, EGFR, and CTSL); and a critical transcription factor of the innate immune signal pathway (IRF5) were among the repressed oncogenic targets engaged in the FMT treatment of CRC. Correlation analysis revealed that their expressions were positively correlated with uncultured_bacterium_o_Mollicutes_RF39, Rikenellaceae_RC9_gut_group, and negatively correlated with Bacillus, Marvinbryantia, Roseburia, Angelakisella, Enterorhabdus, Bacteroides, Muribaculum, and genera of uncultured_bacterium_f_Eggerthellaceae, uncultured_bacterium_f_Xanthobacteraceae, Prevotellaceae_UCG-001, uncultured_bacterium_f_Erysipelotrichaceae, uncul-tured_bacterium_f_Lachnospiraceae, uncultured_bacterium_f_Ruminococcaceae, Eubacterium_coprostanoligenes_group, Ruminococcaceae_UCG-005, and uncultured_bacterium_f_Peptococcaceae. This study provides more evidence for the application of FMT in the clinical treatment of CRC.

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Lymphadenectomy for Colorectal Cancer: Experience of the Brazzaville Teaching Hospital

Cited by 2 publications

References 41 publications

Laparoscopic Appendectomies at Brazzaville University Hospital

Laparoscopic Appendectomies at Brazzaville University Hospital

Suppressed oncogenic molecules involved in the treatment of colorectal cancer by fecal microbiota transplantation

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