Lymphadenopathy

Sahai, Shashi

doi:10.1542/pir.34.5.216

Cited by 8 publications

(2 citation statements)

References 7 publications

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“…Localized lymphadenopathy was defined as enlarged lymph nodes in a single or 2 contiguous anatomical areas, and generalized lymphadenopathy was defined as the presence of lymphadenopathy in 2 or more non-contiguous anatomical areas (23,26).…”

Section: Methodsmentioning

confidence: 99%

Association Between Clinical, Laboratory, and Ultrasound Characteristics and Cancer Incidence of Peripheral Lymphadenopathy in Children

TERZİ,

ÇELİK,

ALKHABBAZ

et al. 2024

Mitteilungen Klosterneuburg

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Objective: Peripheral lymphadenopathy is very common in childhood. Although they are usually benign, they are often seen in pediatric outpatient clinics because they are a major cause of concern for families. However, physicians cannot afford to overlook the possibility of cancer, which is why many of these patients are referred to pediatric hematology and oncology outpatient clinics. In this study, we calculated the proportion of patients requiring biopsy and the frequency of malignancy, and investigated the characteristics that may be associated with malignancy.

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Section: Methodsmentioning

confidence: 99%

Association Between Clinical, Laboratory, and Ultrasound Characteristics and Cancer Incidence of Peripheral Lymphadenopathy in Children

TERZİ,

ÇELİK,

ALKHABBAZ

et al. 2024

Mitteilungen Klosterneuburg

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“…Localized lymphadenopathy is defined as an abnormality of lymph nodes in only one region (e.g., cervical, inguinal, axillary) and can be unilateral or bilateral. Lymphadenopathy is generalized when lymph nodes are affected simultaneously in two or more noncontiguous regions [1,2].…”

Section: Introductionmentioning

confidence: 99%

Association between the Clinical, Laboratory and Ultrasound Characteristics and the Etiology of Peripheral Lymphadenopathy in Children

Berce,

Rataj,

Dorič

et al. 2023

Children

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Peripheral lymphadenopathy affects most children at least once in a lifetime and represents a major reason for concern. Therefore, we aimed to identify the most common causes of peripheral lymphadenopathy in hospitalized children and to determine the clinical, laboratory and ultrasound characteristics that enable fast, easy and accurate etiological diagnosis. We performed a cross-sectional study including 139 children who were hospitalized because of peripheral lymphadenopathy. Ultrasound of lymph nodes was performed in 113 (81.3%) patients. Lymphadenopathy was generalized in nine (6.5%) patients. Malignant etiology was established in only three (2.2%) patients. Bacterial lymphadenitis, infectious mononucleosis (IM) and cat scratch disease (CSD) were diagnosed in 66 (47.5%), 31 (22.3%) and 29 (20.9%) patients, respectively. Bacterial lymphadenitis was significantly associated with neutrophilia (p < 0.01), and increased C-reactive protein levels (p < 0.01). IM was associated with pharyngitis (p < 0.01), leukocytosis without neutrophilia (p = 0.03) and increased blood liver enzyme levels (p < 0.01). CSD was associated with recent contact with a cat (p < 0.01), absence of a fever (p < 0.01) and normal white blood cell count (p < 0.01). Thorough history and clinical examination in combination with a few basic laboratory tests enable fast and accurate differentiation between the most common etiologies of lymphadenopathy in children to avoid unnecessary procedures and hospitalizations.

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Pathologic etiology and predictors of malignancy in children with cervical lymphadenopathy

et al. 2022

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Lymphadenopathy

Cited by 8 publications

References 7 publications

Association Between Clinical, Laboratory, and Ultrasound Characteristics and Cancer Incidence of Peripheral Lymphadenopathy in Children

Association Between Clinical, Laboratory, and Ultrasound Characteristics and Cancer Incidence of Peripheral Lymphadenopathy in Children

Association between the Clinical, Laboratory and Ultrasound Characteristics and the Etiology of Peripheral Lymphadenopathy in Children

Pathologic etiology and predictors of malignancy in children with cervical lymphadenopathy

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