Lymphangiography in patients with ovarian epithelial cancer.An evaluation of 289 consecutive cases

Abstract

From January, 1973, to June, 1976, 226 patients with palpable ovarian masses were evaluated preoperatively by lymphography. Histology showed 166 cases of malignant epithelial tumors, 26 benign tumors, and 34 malignant special tumors (not included in this report). Furthermore, the group of patients included 99 recurrences of ovarian epithelial cancer and 24 patients who underwent restaging diagnostic procedures without clinical evidence of disease. Lymphography was negative in all patients with benign tumors. In the 289 cases of epithelial cancer, lymphangiography gave evidence of nodal metastases in 88 (30%). When the histological subtype was considered, the highest incidence of metastases was in undifferentiated carcinoma (50%) and the lowest, in mesonephroid carcinoma (14%). According to the stage before lymphography, nodal metastases were found in 8% of Stage I, 0% of Stage II, 29% of Stage III, and 53% of Stage IV cases. The incidence of metastases was 46% in patients studied for recurrent disease and 17% in patients studied for restaging. Fifty-four percent of patients had metastases only in the pelvic nodes and 18% only in the para-aortic chains; in 28% both chains were involved simultaneously. Bilateral involvement was found in 63% of the positive cases. Retroperitoneal node biopsies were performed in 68 patients (36%). The radiologic/histologic correlation was 100% in the lymphangiographically positive cases; 81% in the negative cases, with nine false-negative reports; and 87% in all cases.

Ovarian cancer initially presenting with isolated ipsilateral superficial inguinal lymph node metastasis: a case study and review of the literature

“…The incidence of inguinal lymph node metastasis in ovarian carcinoma was approximately 3-5% as reported in literatures [6,11,13,14], while these studies can't provide enough clinical informations and pathological features. A little bit more detailed descriptions include following cases.…”

Surgical implications of mesenteric lymph node metastasis from advanced ovarian cancer after bowel resection

“…Although not all patients underwent retroperitoneal and pelvic lymphadenectomy, a route of dissemination from the mesentery directly to the retroperitoneal node without involvement of the pelvic nodes might exist. Nevertheless, lymphatic drainage of the ovaries via the infundibulopelvic ligament is still regarded as the chief pathway 45.…”

Rare Distant Metastatic Disease of Ovarian and Peritoneal Carcinomatosis: A Review of the Literature

“…Musumeci et al examined 349 patients with ovarian cancer identifying lymph node metastases in 25% of them. Only three of these patients (0.8% of the total participants) had inguinal lymph node involvement that was histopathological confirmed [99]. Zaren et al published a retrospective analysis of 2232 patients with ovarian cancer and inguinal lymph node metastases.…”