Lymphatic disorders after renal transplantation: new insights for an old complication

Ranghino, Andrea; Segoloni, Giuseppe; Lasaponara, F.; Biancone, Luigi

doi:10.1093/ckj/sfv064

Cited by 96 publications

(85 citation statements)

References 90 publications

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“…There are several reports and new techniques to overcome this important issue. [12][13][14] However, as Sood et al [7] previously explained, because of the transperitoneal approach, with our technique, this important complication does not occur.…”

Section: Discussionmentioning

confidence: 91%

Robotic kidney transplantation: The Bakırköy experience

Tuğcu

Şener

Şahin

et al. 2016

Turkish Journal of Urology

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Objective: Robotic kidney transplantation, first described by Hoznek and colleagues, and has been improved by investigators like Oberholzer and Menon. We realized the first robotic kidney transplant (RKT) in our clinic in December 2015. In this study, we aimed to present the first 15 cases we performed within 3 months. Materıal and methods:Starting from January 2016, we performed 15 RKTs in our hospital. Before surgery, the whole robotic procedure was thoroughly explained to the patients and their informed consents were taken. Results:We performed RKT in 7 male and 8 female patients. Mean patient age was 37.4±10.8 years. Mean body mass index of the patients was 22.6±3.35 kg/m². Mean preoperative creatinine and hemoglobin levels were 6.14±2.12 mg/dL and 10.04±1.64 g/dL, respectively. Mean operative time was 300.3±104.2 minutes. Mean warm ischemia and re-warming times were 1.9±0.54 minutes and 73.3±30.7 minutes, respectively. We did not need any necessity to switch to open surgery, and any intraoperative complication did not develop in any patient. Lymphocele which is one of the most frequently encountered complications was not observed in our series. Conclusion:We think that using a minimally invasive approach greater number of patients will be able to benefit from this treatment modality, and this important health issue may decrease significantly.

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Section: Discussionmentioning

confidence: 91%

Robotic kidney transplantation: The Bakırköy experience

Tuğcu

Şener

Şahin

et al. 2016

Turkish Journal of Urology

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“…There is evidence that m-TOR inhibitors interfere with the activation of lymphatic endothelial cells by vascular endothelial growth factors (VEGF)-C and antilymphangiogenic activity is a general phenomenon of m-TOR inhibition 9 10…”

Section: Discussionmentioning

confidence: 99%

Late spontaneous decapsulation of the kidney graft in a patient with hepatitis C and treated with sirolimus: possible pathophysiological association in a rare complication

et al. 2017

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Late decapsulation with fluid collection is a rare complication of renal transplantation with deleterious effects on kidney function. Its physiopathology is unclear but there might be an association with mammalian target of rapamycin (m-TOR) inhibitors, especially in patients with chronic hepatitis C. We report a case of late spontaneous decapsulation 12 years after kidney transplant in a patient infected with hepatitis C under treatment with sirolimus. He underwent marsupialisation of the collection, sirolimus was converted to cyclosporine and hepatitis C treatment was performed with success. This is the first successful case report of late spontaneous decapsulation of the kidney graft in a patient with hepatitis C.

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“…Patients are usually asymptomatic, and spontaneous resolution occurs after a few months. [32][33][34][35][36] The incidence of symptomatic lymphoceles after kidney transplant in our center has been 4.2% (109/2594 total cases). This complication presented with elevated serum creatinine levels in 31 patients (28.4%), pain and abdominopelvic swelling in 53 patients (48.6%), and lower extremity edema in 25 patients (22.9%).…”

Section: Lymphocelesmentioning

confidence: 93%

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2016

Exp Clin Transplant

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Since the first successful organ transplant conducted between twins in 1954, kidney transplant has evolved considerably over the past 50 years. Kidney transplant plays an important role in the treatment of end-stage kidney disease to improve the quality of life and prolong the life of patients. Despite significant advances, postoperative medical and surgical complications still represent important causes of morbidity and mortality. Many problems can be avoided through prophylactic correction of abnormalities detected during the preoperative evaluation; however, it is critical that technical mishaps at all stages of the transplant process (donor nephrectomy, benchwork preparation, and implant) be prevented and that careful postoperative monitoring be carried out, including thorough examination by attending physicians. However, despite these advances, surgical complications still present serious problems in kidney transplant recipients.

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Lymphatic disorders after renal transplantation: new insights for an old complication

Cited by 96 publications

References 90 publications

Robotic kidney transplantation: The Bakırköy experience

Robotic kidney transplantation: The Bakırköy experience

Late spontaneous decapsulation of the kidney graft in a patient with hepatitis C and treated with sirolimus: possible pathophysiological association in a rare complication

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