Lymphatic filariasis vaccine development: neglected for how long?

Chavda, Vivek P.; Pandya, Anjali; Pulakkat, Sreeranjini; Soniwala, Moinuddin; Patravale, Vandana

doi:10.1080/14760584.2021.1990760

Cited by 9 publications

(1 citation statement)

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“…Global concerns arise from the notion that overall living conditions and mobility contribute to heightened susceptibility to elevated microfilaremia levels in certain populations compared to others [ 5 ]. The development of an effective long-term prophylactic strategy, which includes the implementation of a vaccine, is crucial for limiting and eventually eradicating LF in endemic regions [ 10 ]. Filariasis treatment typically involves a combination of drugs such as diethylcarbamazine, ivermectin, and albendazole.…”

Section: Introductionmentioning

confidence: 99%

Unraveling Lymphatic Filariasis in an Old Man: A Case Report

Handa,

Gaidhane,

Choudhari

2024

Cureus

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Lymphatic filariasis, caused by filarial worms such as Wuchereria bancrofti, Brugia malayi, and Brugia timori, represents a significant public health burden in endemic regions. The disease primarily affects the lymphatic system, leading to lymphatic dysfunction and chronic morbidity. This abstract provides a comprehensive overview of lymphatic filariasis, including its transmission dynamics, pathogenesis, clinical manifestations, diagnostic approaches, and treatment options. Special attention is given to the socioeconomic impact of the disease and the challenges associated with its control and elimination. The patient in this particular case is a 58-year-old man who had lower limb swelling and pain, characteristic of chronic lymphatic obstruction. Additionally, the swelling tends to worsen during the evening hours often resulting in difficulty in walking and discomfort. Lymphatic filariasis was diagnosed based on clinical presentation.

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Section: Introductionmentioning

confidence: 99%