Lymphaticovenular Anastomosis for Persistent Immunosuppressant-Related Eyelid Edema

Koshima, Isao; Imai, Hirofumi; Yoshida, Shuhei; Nagamatsu, Shogo; Yokota, Kazushige; Mizuta, Haruki; Harima, Mitsunobu; Yamashita, Shuji; Tom, Laura K.; Kannan, Ruben Y.

doi:10.24983/scitemed.imj.2018.00090

Cited by 4 publications

(4 citation statements)

References 17 publications

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“…LVA was first developed by Yamada [ 14 ] and O’Brien et al [ 15 , 16 ]. However, recent technological advances in LVA and supermicrosurgery have been developed by Koshima et al [ 17 ], and numerous studies support LVA as firstline therapy in lymphedema patients. Numerous papers have demonstrated LVA to be effective in the upper and lower extremities.…”

Section: Discussionmentioning

confidence: 99%

Lymphaticovenular anastomosis for Morbihan disease: a case report

Hong

Lee

et al. 2023

Arch Craniofac Surg

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Morbihan disease (MD) is a very rare condition characterized by rosaceous or erythematous lymphedema on the upper twothirds of the face. A definitive management strategy for MD is lacking, and treatment is challenging. Herein, we present a case of persistent bilateral eyelid edema treated by lymphaticovenular anastomosis (LVA) and lymph node-vein bypass surgery. The patient experienced persistent bilateral eyelid edema. Indocyanine green lymphography was performed, and the diagnosis of bilateral facial lymphedema was confirmed. On the right side, a preauricular lymphatic vessel was anastomosed to a vein. On the left side, lymphostomy on the preauricular lymph node was done, with anastomosis to the transected proximal end of the concomitant vein of the transverse facial artery. Furthermore, a preauricular lymphatic vessel was anastomosed to a vein. Eyelid edema decreased and progressively improved on both sides. The outcome of this case suggests that LVA and lymph node-vein bypass surgery are appropriate for treating persistent eyelid edema related to MD.

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Section: Discussionmentioning

confidence: 99%

Lymphaticovenular anastomosis for Morbihan disease: a case report

Hong

Lee

et al. 2023

Arch Craniofac Surg

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“… 3 LVA has recently been indicated as a treatment option for a wider range of illnesses, such as coexisting Raynaud’s phenomenon and lymphedema, morbidly obese patients with lymphedema, and immunosuppressant-induced lymphedema. 8 – 10 Currently, only conservative methods have been used for the treatment of rheumatoid lymphedema. 2 Surgical treatment might be considered in patients that are refractory to conservative treatment.…”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Rheumatoid Lymphedema with Lymphatic Venous Anastomosis

Imai

Yoshida

Uchiki

et al. 2021

Plastic and Reconstructive Surgery - Global Open

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Summary: Rheumatoid lymphedema is a rare but severely disabling condition caused by reduced lymphatic drainage. Most treatment methods are conservative and may lead to the exacerbation of lymphedema. Lymphatic venous anastomosis (LVA) is an effective treatment for lymphedema after surgery involving the lymphatic system, such as lymph node dissection for cancer treatment. LVA has not been used to treat rheumatoid lymphedema. We present a case of rheumatoid lymphedema treated with surgical procedures, including LVA. Following LVA, objective and subjective symptom relief was noted, along with decreased swelling and pain in the affected area. The postoperative course was uneventful. LVA for the treatment of rheumatoid lymphedema may provide definitive clinical improvements.

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“…Functional evaluation of the facial lymphedema using indocyanine green lymphography is helpful for evaluating lymphatic function and planning lymphatic surgery ( Fig. 2 ) [ 12 ].…”

Section: Diagnosismentioning

confidence: 99%

“…Based on this evidence, lymphatic drainage surgery is applicable to the treatment of MD. For lymphatic bypass surgery for the treatment of periorbital edema, drainage can be achieved by anastomosis of a subdermal venule with a lymphatic collecting vessel in the preauricular region [ 12 ]. In addition to the lymphatic collecting vessels, there are lymph nodes in the preauricular region that can be shunted to venous drainage using a nodal-venous anastomosis to the facial vein.…”

Section: Treatmentmentioning

confidence: 99%