Lymphedema in ovarian cancer survivors: Assessing diagnostic methods and the effects of physical activity

Iyer, Neel S.; Cartmel, Brenda; Friedman, L. F.; Li, Fangyong; Zhou, Yang; Ercolano, Elizabeth; Harrigan, Maura; McCorkle, Ruth; Schwartz, Peter E.; Irwin, Melinda L.

doi:10.1002/cncr.31239

Cited by 24 publications

(24 citation statements)

References 27 publications

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“…However, research examining the PA role in subjects with LLL secondary to cancer treatment is scant [18]. Only a few studies reported the occurrence of adverse effects due to the practice of physical exercise, though a possible benefit to the affected lower limb is not yet well established [18,23]. In this context, a study has evaluated the effect of an eight-week supervised progressive weight training, followed by three months unsupervised, on leg swelling and functional mobility as well as QoL in subjects with secondary LLL [18].…”

Section: Discussionmentioning

confidence: 99%

Role of a Structured Physical Activity Pathway in Improving Functional Disability, Pain and Quality of Life in a Case of Breast and Gynecological Cancer Survivorship

Mirandola

Muraca²,

Sgambati

et al. 2019

JCM

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Physical activity (PA) interventions can improve physical functioning, treatment-related symptoms and quality of life (QoL) in cancer survivors. Most investigations have been conducted in breast cancer survivors, while studies on PA interventions in gynecological cancer survivors are scant. Here, we report for the first time the possible benefits of a structured PA pathway (i.e., eight weeks of adapted PA followed by twelve weeks of adapted fitness) on physical side effects, pain and QoL in an uncommon case of survivorship of both primary breast and gynecological cancers. For this purpose, a 69-year-old woman was assessed by functional test battery (shoulder–arm mobility, range of motion, back flexibility) at baseline and after the structured PA pathway. QoL and surgical shoulder, back and lower limb pain intensity were evaluated by Short Form-12 (SF-12) and numerical rating scale questionnaires, respectively. Lower limb circumference was also assessed. Improvement in upper limb function, reduction of lower limb edema and pain perception, as well as an increase in overall QoL were achieved after the completion of structured PA intervention. Our findings suggest that a PA intervention tailored to individual characteristics may represent an effective countermeasure to reduce post-treatment functional disability and pain, and thus to improve QoL in breast and gynecologic cancer survivors.

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Section: Discussionmentioning

confidence: 99%

Role of a Structured Physical Activity Pathway in Improving Functional Disability, Pain and Quality of Life in a Case of Breast and Gynecological Cancer Survivorship

Mirandola

Muraca²,

Sgambati

et al. 2019

JCM

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“…Outcomes evaluated in trials have also broadened. There is now trial evidence (again of varying strength) regarding the potential positive effect of exercise for more contemporary treatmentrelated side effects, such as chemotherapy-induced peripheral neuropathy, 18 myalgia and arthralgias, 19,20 lymphoedema (upper-and lower-limb), 21,22 bone health, 23-25 sarcopenia 26,27 and metabolic syndrome, 28 sleep quality, 29 cachexia, 30 cognitive impairment 31 and cardiotoxicity, 32,33 as well as outcomes particularly relevant to the clinical and public health setting, such as treatment adherence or completion [34][35][36] and cost-effectiveness. 37 In the past five years, preliminary findings have also become available from phase 2 exploratory studies that have reported the effect of exercise on survival outcomes.…”

Section: Evidence Of Exercise Benefit Following a Cancer Diagnosismentioning

confidence: 99%

The Exercise and Sports Science Australia position statement: Exercise medicine in cancer management

Hayes

Newton

Spence

et al. 2019

Journal of Science and Medicine in Sport

362

366

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Objectives: Since Exercise and Sports Science Australia (ESSA) first published its position statement on exercise guidelines for people with cancer, there has been exponential growth in research evaluating the role of exercise pre-, during and post-cancer treatment. Design and Methods: The purpose of this report is to use the current scientific evidence, alongside clinical experience and exercise science principles to update ESSA's position statement on cancer-specific exercise prescription. Results: Reported in this position statement is a summary of the benefits accrued through exercise following a cancer diagnosis and the strengths and limitations of this evidence-base. An exercise prescription framework is then proposed to enable the application of cancer-specific considerations for individualisation, specificity, safety, feasibility and progression of exercise for all patients. Additional specific exercise prescription considerations are provided for the presence of haematological, musculoskeletal, systemic, cardiovascular, lymphatic, gastrointestinal, genitourinary and neurological disease-and treatment-related concerns, as well as presence of co-morbid chronic disease. Further, we also identify and discuss cancer-specific pragmatic issues and barriers requiring consideration for exercise prescription. Conclusions: While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients. Targeted exercise prescription, which includes the provision of behaviour change advice and support, is needed to ensure greatest benefit (as defined by the patient) in the short and longer term, with low risk of harm.

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“…There is scant research that has determined the level of physical activity in LLL patients during the treatment of cancer [ 15 , 57 ].…”

Section: Discussionmentioning

confidence: 99%

Comprehensive Decongestive Therapy as a Treatment for Secondary Lymphedema of the Lower Extremity and Quality of Life of Women After Gynecological Cancer Surgery

et al. 2020

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Lymphedema in ovarian cancer survivors: Assessing diagnostic methods and the effects of physical activity

Cited by 24 publications

References 27 publications

Role of a Structured Physical Activity Pathway in Improving Functional Disability, Pain and Quality of Life in a Case of Breast and Gynecological Cancer Survivorship

Role of a Structured Physical Activity Pathway in Improving Functional Disability, Pain and Quality of Life in a Case of Breast and Gynecological Cancer Survivorship

The Exercise and Sports Science Australia position statement: Exercise medicine in cancer management

Comprehensive Decongestive Therapy as a Treatment for Secondary Lymphedema of the Lower Extremity and Quality of Life of Women After Gynecological Cancer Surgery

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