Lymphocyte-to-Monocyte Ratio is Independently Associated with Progressive Infarction in Patients with Acute Ischemic Stroke

Mao, Xiaocheng; Yu, Qiulong; Liao, Yunfang; Huang, Qin; Luo, Si; Li, Shumeng; Qiu, Yuexin; Wu, Yuhang; Zhang, Jinchong; Chen, Qianxi; Zhu, Ming; Li, Huihua; Lin, Jing; Hong, Daojun

doi:10.2139/ssrn.4097962

SSRN Journal

2022

DOI: 10.2139/ssrn.4097962

|View full text |Cite

Lymphocyte-to-Monocyte Ratio is Independently Associated with Progressive Infarction in Patients with Acute Ischemic Stroke

Xiaocheng Mao

Qiulong Yu

Yunfang Liao

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Association of the Neutrophil-to-Lymphocyte Ratio with 90-Day Functional Outcomes in Patients with Acute Ischemic Stroke

Chen,

Zhang,

et al. 2024

Brain Sciences

View full text Add to dashboard Cite

The neutrophil-to-lymphocyte ratio (NLR), an inflammatory marker, plays an important role in the inflammatory mechanisms of the pathophysiology and progression of acute ischemic stroke (AIS). The aim of this study was to identify the potential factors associated with functional prognosis in AIS. A total of 303 AIS patients were enrolled in this study; baseline information of each participant, including demographic characteristics, medical history, laboratory data, and 90-day functional outcome, was collected. Multivariate logistic regression analysis revealed that NLR, systolic blood pressure (SBP) and National Institutes of Health Stroke Scale (NIHSS) score were found to be independent factors for poor functional outcomes. Receiver operating characteristic (ROC) curve analysis was performed to estimate the predictive value of the NLR for 90-day functional outcome, with the best predictive cutoff value being 3.06. In the multivariate logistic regression analysis, three models were constructed: Model 1, adjusted for age, sex, SBP, and TOAST classification (AUC = 0.694); Model 2, further adjusted for the NIHSS score at admission (AUC = 0.826); and Model 3, additionally adjusted for the NLR (AUC = 0.829). The NLR at admission was an independent predictor of 90-day prognosis in patients with AIS. The risk factors related to poor 90-day functional outcomes were higher SBP, higher NLR, and a greater NIHSS score.

show abstract

Association of the Neutrophil-to-Lymphocyte Ratio with 90-Day Functional Outcomes in Patients with Acute Ischemic Stroke

Chen,

Zhang,

et al. 2024

Brain Sciences

View full text Add to dashboard Cite

show abstract

İskemik İnmenin Etyolojiye Göre Alt Gruplarında Monosit/Hdl-K Oranlarının Karşılaştırılması

GÜNDÜZ

2023

Genel Tıp Dergisi

View full text Add to dashboard Cite

Abstract Background/Aim:The increase in (MHR) values calculated by the ratio of monocyte to high-density lipoprotein cholesterol (HDL-C) is a parameter that has recently been evaluated as a measure of inflammation and oxidative stress.There are data associated with cardiovascular diseases and carotid artery pathologies.The aim of this study is to seek an answer to the question "Can MHR be a guiding parameter in the differentiation of these pathologies that are blamed in the etiology of ischemic stroke?" Methods:The records of 200 patients with the diagnosis of acute ischemic stroke and whose neurological examination, neuroradiological imaging and monocyte and HDL-C examinations were completed within the first 24 hours after the onset of symptoms were evaluated retrospectively. They were grouped according to the TOAST classification.Measured monocyte values, HDL-C values and MHR values obtained by monocyte/HDL-C ratio were analyzed statistically according to TOAST groups, comorbid diseases and gender. Results:There was a statistically significant increase in MHR in male and in diabetics, without any statistically significant difference between TOAST groups in terms of MHR. Conclusion:MHR is not an appropriate parameter to use in the estimation of these groups, as it does not show any difference between the subgroups of stroke depending on the etiology.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Lymphocyte-to-Monocyte Ratio is Independently Associated with Progressive Infarction in Patients with Acute Ischemic Stroke

Cited by 2 publications

References 13 publications

Association of the Neutrophil-to-Lymphocyte Ratio with 90-Day Functional Outcomes in Patients with Acute Ischemic Stroke

Association of the Neutrophil-to-Lymphocyte Ratio with 90-Day Functional Outcomes in Patients with Acute Ischemic Stroke

İskemik İnmenin Etyolojiye Göre Alt Gruplarında Monosit/Hdl-K Oranlarının Karşılaştırılması

Contact Info

Product

Resources

About