2018
DOI: 10.1016/j.humpath.2018.02.007
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Lymphocytic colitis: pathologic predictors of response to therapy

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Cited by 10 publications
(10 citation statements)
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“…-The role of the microbiome, significant dysbiosis and reduced diversity in the pathogenesis of IBD and MC is increasingly recognized. -Histopathological images of lymphocytic colitis also show non-squamous granulomas and impaired crypts structure, similar to those observed in Crohn's disease (79). -In MC, the expression of proinflammatory cytokines (e.g., interferon-gamma, tumor necrosis factor-alpha, IL-17, etc.)…”
Section: Directions Of the Cryptic Pathwayssupporting
confidence: 62%
“…-The role of the microbiome, significant dysbiosis and reduced diversity in the pathogenesis of IBD and MC is increasingly recognized. -Histopathological images of lymphocytic colitis also show non-squamous granulomas and impaired crypts structure, similar to those observed in Crohn's disease (79). -In MC, the expression of proinflammatory cytokines (e.g., interferon-gamma, tumor necrosis factor-alpha, IL-17, etc.)…”
Section: Directions Of the Cryptic Pathwayssupporting
confidence: 62%
“…1 Focal and mild damage of the surface epithelium, including flattening, mucin depletion and vacuolisation, is seen, although not as prominently as in CC. 1,3,167,218,220,236,237,240,242,[245][246][247][248] This should be combined with an inflammatory infiltrate in lamina propria of a mild to moderate degree, dominated by plasma cells and lymphocytes, 3,4,167,217,218,220,233,236,238,239,241,242,[246][247][248][249][250][251][252][253][254] but might also include fewer eosinophils and neutrophils. 3,217,220,248,250,254,255 Occasionally, cryptitis 217,220,221,249,252,…”
Section: Diagnosis Of MC What Is the Endoscopic Appearance Of Mc?mentioning
confidence: 99%
“…2,[8][9][10] Further, studies have demonstrated that some patients with microscopic colitis have histologic findings similar to those in IBD. [11][12][13] Last, mucosal gene expression profiling in patients with microscopic colitis resembles that of IBD. 3,14 Despite these lines of evidence, the relationship between microscopic colitis and subsequent risk of IBD remains largely uncharacterized.…”
mentioning
confidence: 99%