Lymphocytic tumours of the conjunctiva

Abstract

SYNOPSIS Twenty-six cases of lymphocytic tumour of the conjunctiva, which were originally classified as benign lymphoma and lymphosarcoma, were followed up for more than five years, They were then reclassified into non-disseminating and disseminating groups van Duyse (1905) who was the first worker to treat the lesions by irradiation, Baslini (1907), Cosmettatos (1910), and Coats Received for publication 12 November 1970. (1915) who described five cases affecting young people. The tumours recorded by Coats were slowly growing and were situated at the inner portion of the conjunctiva, three affecting the plica, one the caruncle, and the fifth affecting the limbus. The lesions were bilateral and symmetrical in one case. Bedell (1922) described the first case in America, and other cases have been described by Speciale-

Erythroderma, an unusual manifestation of B cell lymphoma

“…In their attempt to explain the 'ecotaxis' (De Sousa, 1971) or 'homing' of lymphocytic mahgnancies to non-lymphoid tissues, Goudie et ai (1974) suggested that small numbers of circulating lymphocytes may home on quite sharply defined areas of the body not usually regarded as secondary lymphoid organs. This principle was adduced to explain the symmetrical deposition of lymphomatous lesions which have been described in such organs as the breast (Goudie et ai, 1974), conjunctiva (Morgan, 1971), and testes (Tellem et ai, 1961). In the context of our patient, the disposition of primary cutaneous lymphoma can be explained on the basis of the emergence of a single clone of neoplastic lymphocytes with ecotaxis of a highly tissue-specific nature.…”

Acute Myelomonocytic Leukemia Cutis Presenting as a Conjunctival Lesion

“…Lymphocytic tumors of the conjunctiva are typically small, firm, salmonpink, fleshy, slow-growing, and painless lesions that can be found anywhere in the conjunctiva and that may extend onto the cornea or into the orbit. 6 The conjunctival lesion in our case was a giant papillary reaction of the palpebral conjunctiva. The differential diagnosis for this type of lesion is extensive and includes vernal conjunctivitis, giant papillary conjunctivitis, benign lymphoid hyperplasia, papilloma, amyloidosis, tuberculosis, sarcoidosis, trachoma, coccidioidomycosis, parasites, rheumatoid nodule, herpes simplex conjunctivitis, syphilis, Parinaud's oculoglandular syndrome, and ligneous conjunctivitis.…”

Primary Conjunctival Lymphoma: Response to Chemotherapy in 4 Cases

“…Furthermore, the generalization of DWDLL = Diffuse well-differentiated lymphocytic lymphoma; DPDLL = diffuse poorly-differentiated lymphocytic lymphoma (Rappaport); MLL = malignant lymphoma lymphocytic; MLCcFD = malignant lymphoma centroblastic-centrocytic follicular and diffuse; M LC = malignant lymphoma centroblastic (Kiel); CR = complete response. this peculiar lymphoma [2,3] is similar to early extranodal lymphoma. For these reasons we used chemotherapy according to an original combina tion drug program [1]: adriamycin 40 mg/m!…”