Lymphoepithelioma-Like Carcinoma of the Kidney

Lymphoepithelioma-Like Carcinoma of the Skin: A Report of Two Cases Treated With Complete Microscopic Margin Control and Review of Literature

“…LELCS histologically resembles the lymphoepitheliomatous malignancies that have been described to occur in the nasopharynx, 4 palatine tonsils, 5 salivary glands, 6 lung, 7–9 thymus, 10 gastrointestinal tract, 11,12 kidney, 13,14 ureter, 15,16 urinary bladder, 17 breast, 18 and uterine cervix 19 . Microscopic examination reveals a multifocal distribution of tumor involving the mid to reticular dermis and occasionally the subcutis and skeletal muscle 1,20 .…”

Lymphoepithelioma‐like carcinoma of the renal pelvis

“…LELC is morphologically identical to nasopharyngeal carcinoma, and has also been described in the salivary glands, thymus, lung, stomach, skin and cervix. It is rarely seen in the urinary tract, with only isolated cases involving the urinary bladder, 1,4 ureter, 5 and kidney 6,7 . To our knowledge, four patients with LELC of the renal pelvis have been reported previously 8,9 .…”

Lymphoepithelioma-like Carcinoma of the Renal Pelvis–A Case Report and Literature Review

“…In situ hybridization was performed for EBV (PNA, Dako) but failed to demonstrate the presence of EBV in the tumor cells or adjacent renal epithelial cells [13]. Elzevie et al [16] reported Computerized tomography (CT) demonstrated a 3.5 cm×3 cm. tumor in the left kidney with positive lymph nodes.…”

“…A tumor in the lower pole measuring 5.5 cm greatest diameter reached the renal pelvis and infiltrated the perirenal hilar fatty tissue. Immunostaining for Epstein-Barr virus was weakly positive [16].…”

“…So far, 8 cases of kidney of LELC have been reported [7,[9][10][11][12][13][14][15], except one in the kidney, another seven cases in the renal pelvis. Reports with complete CT images at present in abroad are only three [10,13,16].…”