Lymphoid reaction in chlamydial endometritis.

Thomas, G D

doi:10.1136/jcp.39.4.464-a

Cited by 1 publication

(3 citation statements)

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“…The lymphoma‐like lesion possibly represents an antigen‐stimulated proliferation of this endometrial‐associated lymphoid tissue. Epstein‐Barr virus (Young et al 1985) and C. trachomatis (Thomas 1986) have been suggested as possible triggering antigens.…”

Section: Discussionmentioning

confidence: 99%

“…We cannot judge whether this occurrence is higher than expected since there have been no systematic studies of the prevalence of these changes in the endometrium. For example, Thomas (1986) reported a case of immunoreaction associated with C. trachomatis which was later reclassified as C. endometritis, but Young (1985) reported 16 cases (including non‐endometrial cases) of which four were classified as malignant lymphoma.…”

Section: Discussionmentioning

confidence: 99%

“…So far descriptions of only seven such endometrial lesions have been published: five reported by Young et al (1985), a case report by Larsen et al (1981) and another case report by Thomas (1986). An infectious aetiology is suggested by Young et al (1985) (Epstein‐Barrvirus) and Thomas (1986) (Chlamydia trachomatis). We review the histopathology and clinical course of 29 patients with such lymphoma‐like lesions of the endometrium and argue in favour of the use of the term immunoreactive endometritis for this histological entity.…”

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confidence: 99%

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Immunoreactive endometritis

SKENSVED¹,

HANSEN²,

VETNER³

1991

BJOG

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Summary. A benign polyclonal lymphoid proliferation of the endometrium which bears morphological resemblance to the malignant lymphoma is found among women with bleeding disturbances. Seven previous cases have so far been reported in the literature. A retrospective examination of 11648 endometrial specimens revealed 287 examples of chronic endometritis (2–5%) of which 29 displayed lymphoid proliferation. We found no evidence of malignant haematologic disorder after a median observation of 68 months and no positive association with prior or present infectious disease. Histological follow‐up of ten patients showed that changes could persist for up to 12 months. We name this benign condition ‘immunoreactive endometritis’.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%