Lymphoma at uncommon sites

Young, G. A. R.

doi:10.1002/(sici)1099-1069(199906)17:2<53::aid-hon638>3.0.co;2-s

Cited by 14 publications

(6 citation statements)

References 267 publications

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“…Primary extranodal disease with a single pelvic mass without systemic involvement is a rare condition. 2 If lymphoma arises in a single organ and confined to the adjacent lymphoid tissue, it is termed as primary. In the presence of more than one afflicted organ or extranodal site, or involvement of nodes other than just contiguous with primary organ, it is termed as secondary.…”

Section: Discussionmentioning

confidence: 99%

Primary Extranodal Hodgkin's Lymphoma presenting with a Single Pelvic Mass

Kiran¹,

Canaz²,

Sayar³

et al. 2014

Journal of South Asian Federation of Obstetrics and Gynaecology

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Introduction: Although lymphomas can arise from a wide variety of tissues, primary extranodal presentation is predominantly a feature of non-Hodgkin's lymphomas. Primary pelvic extranodal Hodgkin's lymphoma is a rare malignancy. We presented a case of primer retroperitoneal Hodgkin's lymphoma initially presumed gynecologic malignancy. We discussed its rarity, staging and management.Case report: A 75-year-old woman was referred to our hospital with persisting pelvic mass. Pelvic examination revealed an ill-defined immobile mass with hard in consistency. The mass 100 × 75 mm in diameter, invading right parametrium, perivesical space and bladder wall was detected in CT and there were no signs of metastases or enlarged lymph nodes. Diagnostic laparoscopy was suggested but the patient refused the surgery due to her advanced age. One year later, she presented with the symptoms of fever, sweats and fatigue. Hodgkin's lymphoma was diagnosed via laparoscopic biopsy of the mass located at retroperitoneal space anteriorly to the uterus. CT examination revealed multiple swollen lymph nodes and a pulmonary nodule; thus, stage 4 disease was established. International prognostic score was 2, indicating 67% progression free survival; however, patient died due to respiratory failure after the first course of ABVD chemotherapy. Conclusion:Although gynecologists rarely experience primary extranodal lymphomas particularly Hodgkin's disease, lymphoid malignancies should be kept in mind in differential diagnosis of pelvic masses. This disease can rarely arise adjacent to gynecologic organs in retroperitoneal space, and this presentation can be misinterpreted as a gynecological malignancy.

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Section: Discussionmentioning

confidence: 99%

Primary Extranodal Hodgkin's Lymphoma presenting with a Single Pelvic Mass

Kiran¹,

Canaz²,

Sayar³

et al. 2014

Journal of South Asian Federation of Obstetrics and Gynaecology

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“…1) Fidias P et al described primary tracheal lymphoma in only six cases in a review study published in 1999. 4) Furthermore, from 1989 to 2005, only three cases of primary tracheal non-Hodgkin's lymphoma were reported with literature review in Medline. 7) In histological classification of primary tracheal lymphoma, the more common types are lymphoblastic lymphoma and mucosa-associated lymphoid tissue lymphoma.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, there is wide variation in the geographic incidence of extranodal NHL, with reports ranging from 24 percent in the USA to 13 to 48 percent in Italy. 4) The majority of extranodal lymphomas arising from the mucosa-associated lymphoid tissue are B-cell lymphomas of follicle center cell origin. 5) A few cases of extranodal NHL have been reported from Korea, but reports of primary malignant lymphoma of the trachea are extremely rare.…”

Section: Introductionmentioning

confidence: 99%

A Case of Primary Tracheal Lymphoma of a 65-year-old Female: Extremely Rare Primary Localization of a Diffuse Large B-cell Lymphoma

Lim

Yang

et al. 2007

Korean J Hematol

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Primary extranodal non-Hodgkin's lymphomas comprise approximately 10% of all non-Hodgkin's lymphomas. However, primary tracheal non-Hodgkin's lymphoma is extremely rare, being mainly mucosa-associated lymphoid tissue lymphoma. A 65-year-old female has dry cough for one year. She was diagnosed as diffuse large B-cell lymphoma via bronchoscopic-guided biopsy. She was treated with four cycles of the R-CHOP regimen and adjuvant radiotherapy. After completion of the combined treatment, the treatment response was complete remission, and the disease free survival was 26 months.

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“…1 As lymph nodes are distributed throughout the body, lymphomas may manifest with involvement in various areas. 2 This can cause difficulties in diagnosis as well as delayed treatment.…”

Section: Introductionmentioning

confidence: 99%

Rare Clinical Sign of Hodgkin’s Lymphoma: Ocular Involvement

Ayhan¹,

Karabağ²,

Alacacıoğlu³

et al. 2017

tjo

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Bilateral non-granulomatous anterior uveitis with left vitritis and macular edema were detected in a 19-year-old woman presenting with blurred vision in her left eye. Light microscopic study of the pathologic mediastinal lymph node that was detected via contrast computed tomography imaging during etiologic study revealed nodular sclerosing and mixed cellularity Hodgkin’s lymphoma (HL). Ocular findings completely resolved with adriablastin, bleomycin, vinblastine, dacarbazine chemotherapy treatment. Herein, it is emphasized that HL should be remembered as one of the differential diagnoses in patients with ocular inflammatory pathologies such as uveitis and vasculitis. The ocular findings of HL are discussed.

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Lymphoma at uncommon sites

Abstract: Lymphoma can often present in unusual situations. This article provides a comprehensive review of the literature in which both non-Hodgkin's lymphoma and Hodgkin's disease are discussed.

Cited by 14 publications

References 267 publications

Primary Extranodal Hodgkin's Lymphoma presenting with a Single Pelvic Mass

Primary Extranodal Hodgkin's Lymphoma presenting with a Single Pelvic Mass

A Case of Primary Tracheal Lymphoma of a 65-year-old Female: Extremely Rare Primary Localization of a Diffuse Large B-cell Lymphoma

Rare Clinical Sign of Hodgkin’s Lymphoma: Ocular Involvement

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