Lymphosarcoma in Indian Zebu Cattle

Abstract

The incidence of bovine lymphosarcoma was studied in 79,492 male adult Indian cattle of 7 different breeds and crossbreeds from one abattoir in Bombay. One of 23,066 Malvi animals, a bullock, was detected with multicentric LS with symmetrically enlarged lymph nodes and spleen. Examination of blood, lymph nodes and spleen confirmed the leukotic condition of the animal. The incidence of bovine LS in India and Western countries is compared, and the interrelationship between leukemia in different species of domestic animals and man is discussed. The need for further epidemiological studies of leukemia in domestic pets and food producing animals in India is suggested.

Nucleolar Organizer Region Count, PCNA and Ki-67 Indices are Diagnostic Markers of Malignancy and Cell Proliferation Rate in Bovine Lymphosarcoma

“…Grossly, the enlargement was noticed in prescapular and precrural lymph nodes in calves and there was enlargement and fusion of mesenteric lymph nodes in the cow. The affected organs were soft, fleshy, greyish white and on cut section, the lymph nodes showed bulging and a homogenous pale appearance with no demarcation between cortex and medulla [14,15,[19][20][21]. Impression smears collected from affected lymph nodes and organs like heart, lung, liver and kidney revealed numerous cells which included lymphocytes, prolymphocytes and lymphoblasts.…”