Lysophosphatidic acid production from lysophosphatidylcholine by lysophospholipase D activity of autotaxin in plasma of women with normal and adverse pregnancies

Tsutsumi, Toshihiko; Yasuda, Katsuhiko; Neya, Mariko; Okada, Hidetaka; Tokumura, Akira

doi:10.1016/j.prostaglandins.2022.106670

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2023

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“…To complement this, a study has shown that LPC levels in pregnancy increase in the first term post conception but decrease to below not-pregnant levels in the second trimester, decreasing further in the third. 44 In addition, other studies have shown increasing concentrations of PC in maternal plasma as gestation progresses, [45][46][47] most likely to ensure an adequate supply for the fetus. This could also be due to the recommended supplementation of phosphatidylcholine during pregnancy, as studies have shown supplementation positively influences fetal development and child behaviour.…”

Section: Discussionmentioning

confidence: 99%