2009
DOI: 10.1002/mnfr.200800161
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Lysozyme in wine: A risk evaluation for consumers allergic to hen's egg

Abstract: Lysozyme used in wine production could present a risk for consumers allergic to hen's egg. Thus, precautionary labeling of lysozyme on wines has been adopted within the European Community by updating Annex IIIa by Directive 2007/68/EC on November 27, 2007. Since no scientific data is known about the actual amounts and risks of lysozyme in wines, various in vitro efforts and skin prick tests were applied in this study to evaluate the presence of lysozyme in wines and the reactivity of those residues in allergic… Show more

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Cited by 59 publications
(52 citation statements)
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“…Another important source are protein-based wine additives (e.g., lysozyme, ovalbumin, gelatin, casein) which could pose allergenic-like reactions to consumers [60][61][62]. Most of these proteins have vanished after termination of wine fermentation and subsequent fining procedures.…”
Section: Proteinasesmentioning
confidence: 99%
“…Another important source are protein-based wine additives (e.g., lysozyme, ovalbumin, gelatin, casein) which could pose allergenic-like reactions to consumers [60][61][62]. Most of these proteins have vanished after termination of wine fermentation and subsequent fining procedures.…”
Section: Proteinasesmentioning
confidence: 99%
“…In the wine industry, lysozyme partially replaces sulfites and is added at doses of 250-500 mg/L to inhibit malolactic fermentation and to stabilize the wine afterwards [20,21]. Residual levels of 0.06-327 mg/L were found in lysozyme-treated wines [22,23], while in commercial cheeses, concentrations of 30.8-386.2 mg/kg were found to be present [24]. Lysozyme has also been used as an antibacterial agent during beer production [25], to extend the shelf-life of meat [26] and shrimp [27], as an alternative to antibiotics [28,29] in veterinary medicine or as anti-inflammatory drug in the treatment of wounds and infections [4,30].…”
Section: Properties Of Lysozyme and Its Importance For Daily Lifementioning
confidence: 99%
“…No information is available about the water-soluble milk whey proteins as contaminants in casein preparations used for wine fining, whose permanence could represent a risk to milk-sensitive subjects (Weber et al 2009). …”
Section: Proteins Used In Winemaking and Possible Drawbacks Related Tmentioning
confidence: 99%
“…Some organic winemakers choose not to filter their wines after fining, which could explain the high level of detection of fining agents. Weber et al (2009) investigated a panel of various white wines fined with different caseinate dosages and 61 commercial wines with unknown fining by using an indirect ELISA method. They detected α-and β-caseins residues in white wine samples, even if processes such as bentonite addition or membrane filtration contributed to a significant decrease of casein residues in wines.…”
Section: Reviewmentioning
confidence: 99%