1965
DOI: 10.1111/j.1476-5381.1965.tb01735.x
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LYTIC ACTION OF CHLORPROMAZINE HYDROCHLORIDE ON ESCHERICHIA COLI G. CELLS

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Cited by 6 publications
(1 citation statement)
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“…The mechanism of action of these compounds against bacterial strains could be the following: action on the permeability of the bacterial membrane, blocking the efflux capacity of the bacterial cell, 48 secretion of toxins, 49 reverse resistance to antibiotics, 50 inhibition of bacterial enzymes, and elimination of plasmids from infected Gramnegative bacteria 51 or the lysis of bacteria. 52 In conclusion, the photochemical breakdown schemes of CPZ in aqueous solution during irradiation with a laser beam emitted at 266 nm and the formation of photoproducts have been suggested. The rates of photoproducts formation are influenced by the generation of singlet oxygen and fluorescence emission by CPZ.…”
Section: Discussionmentioning
confidence: 90%
“…The mechanism of action of these compounds against bacterial strains could be the following: action on the permeability of the bacterial membrane, blocking the efflux capacity of the bacterial cell, 48 secretion of toxins, 49 reverse resistance to antibiotics, 50 inhibition of bacterial enzymes, and elimination of plasmids from infected Gramnegative bacteria 51 or the lysis of bacteria. 52 In conclusion, the photochemical breakdown schemes of CPZ in aqueous solution during irradiation with a laser beam emitted at 266 nm and the formation of photoproducts have been suggested. The rates of photoproducts formation are influenced by the generation of singlet oxygen and fluorescence emission by CPZ.…”
Section: Discussionmentioning
confidence: 90%