M protein deposition in the skin: a rare manifestation of Waldenström macroglobulinemia

Oberschmid, B.; Siebolts, Udo; Mechtel, D.; Kreibich, Ute; Beller, Alexandra; Wickenhauser, Claudia

doi:10.1007/s12185-011-0794-y

Cited by 1 publication

(1 citation statement)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cutaneous manifestations are diverse and may consist of urticaria and purpuric rashes, ulcers, bullous lesions and vasculitis. 46 , 47 …”

Section: Differential Diagnosismentioning

confidence: 99%

Cutaneous primary B-cell lymphomas: from diagnosis to treatment

Lima

2015

An. Bras. Dermatol.

View full text Add to dashboard Cite

Primary cutaneous B-cell lymphomas are a heterogeneous group of mature B-cells neoplasms with tropism for the skin, whose biology and clinical course differ significantly from the equivalent nodal lymphomas. The most indolent forms comprise the primary cutaneous marginal zone and follicle center B-cell lymphomas that despite the excellent prognosis have cutaneous recurrences very commonly. The most aggressive forms include the primary cutaneous large B-cell lymphomas, consisting in two major groups: the leg type, with poor prognosis, and others, the latter representing a heterogeneous group of lymphomas from which specific entities are supposed to be individualized over time, such as intravascular large B-cell lymphomas. Treatment may include surgical excision, radiotherapy, antibiotics, corticosteroids, interferon, monoclonal antibodies and chemotherapy, depending on the type of lymphoma and on the type and location of the skin lesions. In subtypes with good prognosis is contraindicated overtreatment and in those associated with a worse prognosis the recommended therapy relies on CHOP-like regimens associated with rituximab, assisted or not with local radiotherapy. We review the primary cutaneous B-cell lymphomas, remembering the diagnostic criteria, differential diagnosis, classification, and prognostic factors and presenting the available therapies.

show abstract

“…Cutaneous manifestations are diverse and may consist of urticaria and purpuric rashes, ulcers, bullous lesions and vasculitis. 46 , 47 …”

Section: Differential Diagnosismentioning

confidence: 99%