“…Surveys have shown that the number of pregnant women carrying the potential gene for thalassemia is currently about 10-15% of all pregnant women, and the prevalence of thalassemia is more pronounced in some Middle Eastern, Indian, and Southeast Asian countries (2). As there is no effective treatment for thalassemia, the symptoms of thalassemia can only be relieved by blood transfusion, which imposes a great burden on the patient's family (3,4). Therefore, timely assessment and prevention of thalassemia during pregnancy can greatly limit the further development of thalassemia (5).…”