Abstract:Apical periodontitis is among the most frequently occurring pathological lesions around the root apex, which can cause alveolar bone defect and tooth loss, even leading to rheumatoid arthritis, cardiovascular diseases, and diabetes. The exactly underlying molecular mechanisms are still evolving. Fat mass and obesity-associated protein (Fto) is the first identified RNA m6A demethylase/eraser that plays key regulatory roles in multiple biological processes. However, it remains unclear whether Fto is involved in … Show more
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