Abstract:Survival of bacteria in acidic environments is critical for pathogens to successfully multiply and infect the gastrointestinal tract. In this study, a metabolomics approach was conducted to understand and explain the effect of pH-induced stress metabolites in Yersinia enterocolitica. Cells were cultured in tryptic soy broth with or without pH adjustment using HCl (pH 6.8 or pH 3, respectively). In this study, we employed untargeted proton nuclear magnetic resonance (1H-NMR) spectroscopy followed by statistical… Show more
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