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Abstract

Background: Pre-eclampsia is one of the most common causes of maternal and fetal morbidity and mortality. It is a systemic disease that affects about 5-7 % of all pregnancies and is the most common, yet least understood disorder of pregnancy. It is a rapidly progressive condition characterized by high blood pressure, platelet aggregation, swelling of the lower extremities and protein in urine. Sudden weight gain, headaches and changes in vision are important symptoms. Materials and Methods: This case-control study was conducted at Department of Biochemistry, Dr PDM Medical College, Amravati(Maharashtra), India. Data was collected from 70 preeclampsia cases and 70 normal healthy pregnant mothers in the Dept. of Obstetrics and Gynaecology. We have selected 70 cases and 70 controls according to our convenience. Cases are pregnant women with preeclampsia and controls are normal healthy pregnant women. Results: The present study includes 70 cases with pregnancy induced hypertension and 70 controls with normal healthy pregnancy. Mean gestational age showed high significance with Mean ± SD of cases at 36.38 ± 4.19 weeks compared to that of controls at 39.62 ± 1.16 weeks with a p value of < 0.001. Mean gestational age showed high significance with Mean ± SD of cases at 36.38 ± 4.19 weeks compared to that of controls at 39.62 ± 1.16 weeks with a p value of < 0.001. Conclusion: Based on the present study, as serum calcium and magnesium levels are low in preeclamptic mothers and considering the high prevalence of preeclampsia, nutritional conditions of pregnant women seems to be of prime importance. Pregnant women should be educated about nutrition during pregnancy and probable risks of inappropriate diet should be informed.