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Abstract

The presentation of this work aims to update readers on issues associated with coating pan (CPN), having applicability in the pharmaceutical field. The coating process (CPR) is an important pharmaceutical unit operation that finds pertinence in various product areas extending from conventional (immediate) release to modified release. The CPR involves the substrate coating by spraying the coating material in liquid medium onto them, kept in motion using either CPN or fluid bed processor (FBP). The FBP is used preferably for coating of multi-particulates and powders and rarely for tablets, while CPNs are used for coating tablets and capsules, thus are in extensive use. Conventional CPNs and perforated coating pan (PPN) are the major categories of the CPNs. The PPNs are preferred for the products that call for improved drying efficiency where the drying efficiency of the drying air (DA) is highest. The perforated pan system (PPNSY) is used in the coating system based on the aqueous solvent, with preference to that based on the volatile organic solvent (VOS). Comprehensive reviews on the technical aspect of CPNs are rare, necessitating this work. Thereupon the information was studied, summarised, and attempted to be presented for convenience and enrichment of the readers. The contained information will be updating pharmaceutical professionals in this regard. INTRODUCTION:Coating is a process in which a dry outer layer of coat is applied over a substrate (commonly solid particle or dosage form) to provide certain benefits over uncoated form, that range from protecting products (from environmental factors such as air, light, temperature, gastric acid 1, 2 , moisture 2 , to simplify production 3, 4 , product identification 4 , 5 ,