Maca (Lepidium meyenii) and yacon (Smallanthus sonchifolius) in combination with silymarin as food supplements: In vivo safety assessment

Valentová, Kateřina; Stejskal, David; Bártek, J; Dvorácková, S; Křen, Vladimı́r; Ulrichová, Jitka; Šimánek, Vilı́m

doi:10.1016/j.fct.2007.10.031

Cited by 64 publications

(65 citation statements)

References 52 publications

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“…In the study of Hermann, Freire andPazos (1997-1998), the value obtained for potassium was 228.2 mg.(100 g) -1 on a wet weight basis of the yacon pulp, higher than that found in the present study. However, Valentová, Frcek and Ulrichová (2001) found the following concentrations of 0.96 copper mg.(100 g) -1 , 0.54 mg.(100 g) -1 manganese, and 0.67 mg.(100 g) -1 zinc in the yacon pulp. In this case, all the yacon pulp minerals had higher concentrations than those in the present study.…”

Section: Resultsmentioning

confidence: 99%

Studies of chemical and enzymatic characteristics of Yacon (Smallanthus sonchifolius) and its flours

et al. 2013

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Due to the importance of studies on yacon related to health, its in natura pulp, in natura peel, pulp flour, and peel flour were chemically analyzed in terms of its centesimal composition, specific minerals, total dietary fiber and fractions, pH, total soluble solids, total titratable acidity, tannins, oxalic acid, and nitrate. The polyphenoloxidase and peroxidase enzymatic activities were evaluated for in natura pulp and peel only. Yacon pulp and peel flour presented average yield of 7.94% and 10.86%, respectively. The in natura pulp presented a higher moisture and carboydrate content and lower lipid, protein, total dietary fiber, and ash than those of the peel flour. The same pattern was observed for pulp flour when compared to peel flour. The highest tannin, nitrate, and oxalic acid levels were found in the peel flour, 15,304.5 mg.kg-1, 1,578.3 mg.kg-1, and 7,925.0 mg.kg-1 (wet weight), respectively. The polyphenoloxidase and peroxidase enzymes presented higher enzymatic activity in the yacon peel. Based on the results obtained, it can be said that the yacon and its derivatives are important dietary carbohydrate and mineral sources and contain antinutritional substance contents lower than those harmful to health.

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Section: Resultsmentioning

confidence: 99%

Studies of chemical and enzymatic characteristics of Yacon (Smallanthus sonchifolius) and its flours

et al. 2013

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“…These findings are supported in previous studies. Valentova et al (22) reported that 90 days of supplementation with silymarin had no effect on BMI in patients su[U+FB00]ering from metabolic syndrome. In addition, based on the results of Hajaghamohammadi et al (23), 140 mg/day silymarin for two months did not change body weight and BMI significantly.…”

Section: Discussionmentioning

confidence: 99%

Effects of Silymarin Supplementation on Leptin, Adiponectin and Paraoxanase Levels and Body Composition During Exercise: A Randomized Double-Blind Placebo Controlled Clinical Trial

Shirali

Mashhadi

Ashtary‐Larky

et al. 2016

Jundishapur J Nat Pharm Prod

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Background: Silymarin has powerful antioxidant properties, but its effects on athletic performance are poorly understood. Objectives: The present study was undertaken to evaluate the effects of 4 weeks of endurance or strength exercise, with or without silymarin, on body composition, paraoxonase (PON), leptin and adiponectin levels in untrained men. Methods: A total of 45 untrained men were divided into 5 groups (n = 9): endurance training with placebo (ET + P), endurance training with 140 mg of silymarin/day (ET + S), strength training with placebo (ST + P), strength training with 140 mg of silymarin/day (ST + S) and placebo (C). Anthropometrical and VO2max measurements and ELISA assay for PON, leptin and adiponectin levels were performed at the beginning and after the 4-week of the study Results: There was a significant decrease in weight and body mass index in the ET + P and ET + S groups and increases in ST + P and ST + S (P < 0.05) groups. Body fat declined in all four trained groups (P < 0.001). Peak oxygen uptake (VO2max) improved in both ET + P and ET + S subjects. Paraoxonase (PON) was increased only in ET + S group (P < 0.05). Adiponectin was increased in all four groups (P < 0.05). Circulating leptin remained unchanged within all interventions. Conclusions:The present study has demonstrated that a combination of exercise and silymarin can improve body composition and adiponectin levels.

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“…Lepidium Meyenii Walp (maca) is an annual or biennial herbaceous crop belonging to the Brassicaceae family, which has been grown and cultivated exclusively in the Junín plateau of Peru's Central Highlands for approximately 2,000 years [1].…”

Section: Introductionmentioning

confidence: 99%

A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen

Stone

Ibarra

Roller

et al. 2009

Journal of Ethnopharmacology

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A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen. Journal of Ethnopharmacology, 126 (3 Northumbria University has developed Northumbria Research Link (NRL) to enable users to access the University's research output. Copyright © and moral rights for items on NRL are retained by the individual author(s) and/or other copyright owners. Single copies of full items can be reproduced, displayed or performed, and given to third parties in any format or medium for personal research or study, educational, or not-for-profit purposes without prior permission or charge, provided the authors, title and full bibliographic details are given, as well as a hyperlink and/or URL to the original metadata page. The content must not be changed in any way. Full items must not be sold commercially in any format or medium without formal permission of the copyright holder. The full policy is available online: http://nrl.northumbria.ac.uk/policies.html This document may differ from the final, published version of the research and has been made available online in accordance with publisher policies. To read and/or cite from the published version of the research, please visit the publisher's website (a subscription may be required.) trial before and after 14 days supplementation with both maca extract (ME) and placebo, in a randomised crossover design. Subjects also completed a sexual desire inventory during each visit. Results: ME administration significantly improved 40 km cycling time performance compared to the baseline test (P = 0.01), but not compared to the placebo trial after supplementation (P >0.05). ME administration significantly improved the self rated sexual desire score compared to the baseline test (P = 0.01), and compared to the placebo trial after supplementation (P = 0.03). Conclusion: 14 days ME supplementation improved 40km cycling time trial performance and sexual desire in trained male cyclists. These promising results encourage long-term clinical studies involving more volunteers, to further evaluate the efficacy of ME in athletes and normal individuals and also to explore its possible mechanisms of action.

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Maca (Lepidium meyenii) and yacon (Smallanthus sonchifolius) in combination with silymarin as food supplements: In vivo safety assessment

Cited by 64 publications

References 52 publications

Studies of chemical and enzymatic characteristics of Yacon (Smallanthus sonchifolius) and its flours

Studies of chemical and enzymatic characteristics of Yacon (Smallanthus sonchifolius) and its flours

Effects of Silymarin Supplementation on Leptin, Adiponectin and Paraoxanase Levels and Body Composition During Exercise: A Randomized Double-Blind Placebo Controlled Clinical Trial

A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen

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