As a pair of closely related technical fields, “Internet of Things” and “big data” are gradually applied to the analysis of online shopping, which is very beneficial to promote the healthy and orderly development of the online shopping industry. This article uses the big data processing technology of the Internet of Things to analyze the influencing factors of online shopping brand sales based on the data collected by online questionnaires. It draws certain rules from it, and provides relevant marketing strategies for online shopping brand sales to assist its market positioning. According to the survey, the five aspects of online evaluation, brand awareness, online shopping community, online public opinion influence of related brands, and other brand information acquisition channels all have an impact on online brand sales. Especially women aged 25–35 will pay attention to online information, and 195 people will not choose to buy from brands with negative news. And during the purchase process, 186 people will check the online reviews of related brand products. Among them, there are 183 men aged 25–35 who will pay attention to online reviews.