2024
DOI: 10.1016/j.eswa.2023.122585
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Machine learning-based radiomics for amyotrophic lateral sclerosis diagnosis

Benedetta Tafuri,
Giammarco Milella,
Marco Filardi
et al.
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Cited by 4 publications
(2 citation statements)
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“…Since high-dimensional data suffer from noise and redundant attributes that may weaken the performance of model training, multivariate logistic regression with the least absolute shrinkage and selection operator (LASSO) and Boruta algorithms with cross-validation were applied to reduce the high dimensionality of features and to select the radiomics features significantly associated with TLE ( 22 ). To discern crucial features from less significant ones, we initially utilized the Boruta feature selection algorithm to identify pertinent attributes within the training dataset.…”
Section: Methodsmentioning
confidence: 99%
“…Since high-dimensional data suffer from noise and redundant attributes that may weaken the performance of model training, multivariate logistic regression with the least absolute shrinkage and selection operator (LASSO) and Boruta algorithms with cross-validation were applied to reduce the high dimensionality of features and to select the radiomics features significantly associated with TLE ( 22 ). To discern crucial features from less significant ones, we initially utilized the Boruta feature selection algorithm to identify pertinent attributes within the training dataset.…”
Section: Methodsmentioning
confidence: 99%
“…In a similar vein, clinical trials for drugs targeting specific proteins would ideally want to recruit patients whose symptoms aren’t driven by a copathology, or at least account for this copathology in stratification. While there has been some work showing radiomics features can be helpful for differential diagnosis in Parkinson’s disease 73 and amylotrophic lateral sclerosis, 74 there is little work exploring potential applications in identifying common copathologies in AD. Finally, radiomics analysis may provide opportunities for validation studies when used in combination with multimodal data where biologically relevant information such as ground truth histopathology ratings are available.…”
Section: The Promise Of Machine Learningmentioning
confidence: 99%