“…This special issue of Industrial & Engineering Chemistry Research presents an excellent collection of articles from internationally renowned researchers from all around the world to showcase the application of machine learning and data science in the aforementioned chemical engineering problems. − We truly appreciate the efforts from all contributing authors to make it happen. We hope these articles provide new insights and perspectives as to how machine learning can be used in a wide variety of chemical engineering problems, and stimulate more creative solutions to existing and future challenges.…”