2024
DOI: 10.21203/rs.3.rs-3924392/v1
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Machine Learning Models identify Signature Genes as potential Biomarkers for Hypertrophic Cardiomyopathy from Williams Syndrome

Hongxiao Yu,
Xiping Liu,
Manfang Sun
et al.

Abstract: Background: Hypertrophic cardiomyopathy(HCM) is a complex genetic cardiovascular disease with the pathogenesis is still unclear. Williams syndrome(WS), an autosomal dominant systemic disorder with the phenotype of series congenital heart disease that caused by the missing of low-copy DNA elements. The association between the HCM and WS remains unrevealed. This study aimed to identify the WS-related genes from a special patient by using bioinformatics analysis to clarify insights into the diagnostic value in HC… Show more

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