Macrocyclic host cyclophosphazenes from aminolysis of N3P3CI6 by bis-(2-ortho-aminophenoxyethyl)ether

Abstract

Aminolysis of N 3 P 3 Cl 6 by an oxodiamine, bis-(2-ortho-aminophenoxyethyl) ether, has been carried out under various experimental conditions and new products with different architectures have been obtained. The reaction in diethyl ether when using a Na 2 CO 3 -water interface process gives the mono-BINO as major product. Reaction on Al 2 O 3 /KOH leads to the spirocyclic compound, while, when the reaction is carried out in toluene in the presence of NEt 3 , a mixture of mono-and di-BINO products are obtained.

Synthesis, Characterization andIn VitroAntibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone ()

“…For the past few years, studies of the coordination chemistry of thiosemicarbazone involved complexes with transition metal ions [ 6 – 8 ]. Organotin(IV) complexes have been the subject of interest for some time because of their biomedical and commercial applications including in vitro and in vivo antitumor activity [ 9 , 10 ]. Many organotin(IV) complexes have been found to be as effective as or even better than traditional anticancer drugs [ 11 – 14 ].…”