Macrodystrophia lipomatosa of the foot

Macrodystrophia lipomatosa of the feet and subcutaneous lipomas

“…Macrodystrophia lipomatosa is a sporadic form of localized progressive overgrowth of mesenchymal elements with a disproportionate increase in fibroadipose tissues [Goldman and Kaye, 1977; Baruchin et al, 1988; Gupta et al, 1992; Sawhney and Berry, 1992; Hildebrandt et al, 1993; Bailey et al, 1997; Soler et al, 1997]. The condition is present at birth and usually occurs along the distribution of the median nerve in the upper limb and plantar nerves in the lower limb.…”

X-ray and computed tomography findings in macrodystrophia lipomatosa of the foot with secondary osteoarthritic changes diagnosed in an elderly female: a case report

“…Macrodystrophia lipomatosa is a nonhereditary, congenital developmental anomaly that results in overall progressive overgrowth of all of the mesenchymal elements of a digit, including the digit itself, as well as the phalanges, nerves, and vessels, resulting in gigantism of single digits, multiple digits, or the entire limb (1,2) . It typically presents in childhood but can occur in late adulthood or (more rarely) in old age.…”

Congenital gigantism of the foot

“…The former describes the lesion of a neural element. The lesion is occasionally differentiated with difficulty from diffuse lipomatosis with bone enlargement, which is mainly a lesion of the subcutis and the muscle in which involvement of the neural elements is secondary [18,19].…”