Macrophages of the sperm granuloma 3 months after vasectomy in the Albino Swiss rat

Tait, C.M.; McGinn, J.S.; Milne, E.W.; Bennett, N.K.; McDonald, Stuart W.

doi:10.1002/1098-2353(2000)13:4<267::aid-ca7>3.0.co;2-x

Cited by 10 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additional screenings in the aftermath of vasectomy pinpoint at the ligation site acute inflammation and augment the expression of transferrin and osteopontin by the vas and epididymal epithelium [ 201 ]. In cases of drug-induced epididymal inflammation, this may pave the path of measuring the induction of pro-inflammatory genes [ 202 ], vasectomy leading to sperm antibodies, and sperm granuloma at least [ 203 ].…”

Section: Discussionmentioning

confidence: 99%

A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota

Doroftei

Ilie

Maftei

et al. 2023

JCM

View full text Add to dashboard Cite

Background: Male contraceptive approaches besides tubal sterilization involve vasectomy and represent the method of choice among midlife men in developing countries thanks to many advantages. However, the subsidiary consequences of this intervention are insufficiently explored since the involved mechanisms may offer insight into a much more complex picture. Methods: Thus, in this manuscript, we aimed to reunite all available data by searching three separate academic database(s) (PubMed, Web of Knowledge, and Scopus) published in the past two decades by covering the interval 2000–2023 and using a predefined set of keywords and strings involving “oxidative stress” (OS), “inflammation”, and “semen microbiota” in combination with “humans”, “rats”, and “mice”. Results: By following all evidence that fits in the pre-, post-, and vasectomy reversal (VR) stages, we identified a total of n = 210 studies from which only n = 21 were finally included following two procedures of eligibility evaluation. Conclusions: The topic surrounding this intricate landscape has created debate since the current evidence is contradictory, limited, or does not exist. Starting from this consideration, we argue that further research is mandatory to decipher how a vasectomy might disturb homeostasis.

show abstract

Section: Discussionmentioning

confidence: 99%

A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota

Doroftei

Ilie

Maftei

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

“…In some studies on rabbits, sperm granulomas were not found. Due to the easily tearable structure of the ductus epididymis in human experiments, it is thought that the rise of pressure hinders the reflection of seminiferous tubules (5,(7)(8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

Comperative Investigation of Structure of Male Genital System of Ductus Deferens Ligation in Rats

Yarar

Ömeroğlu

Şen

et al. 2018

GMJ

View full text Add to dashboard Cite

Objective: We investigated structural and morphological changes in prepubertal and pubertal rat testis and ductus deferens after unilateral vasectomy. Vasectomy is reliable and popular male contraception method, applied widely in the world. Methods: Six pre-pubertal and 6 pubertal male Wistar albino rats were divided into four groups. Unilateral ductus deferens ligation was performed on right ductus deferens of each rat. Right testis and ductus deferens tissues were evaluated as ligation group while left tissues were control groups. Two months after operation, the vas deferens and testes removed to obtain paraffin block sections and morphometric studies carried out with light microscopy. Hematoxylin-eosin staining and vascular endothelial growth factor (VEGF) immunohistochemically staining were applied. Results: Structural and morphological changes and decrease in spermatogenesis process have been observed at testis and ductus deferens tissues of all vasectomized rat. The seminiferous epithelium and the seminiferous tubule diameter were thickened. Degenerative changes have been observed at the epithelial structure of Ductus deferens and among muscle fibers forming the muscle of the Ductus deferens. Moreover, in prepubertal and pubertal vasectomized rat VEGF immunoreactivity was not observed in seminiferous tubule. Conclusion:The unilateral ligation operation can cause damage at ductus deferens and testis tissue in the pre-pubertal and pubertal period.

show abstract

Immunopathology of the Male Reproductive Tract

Picut

Rijk

Dixon

2017

Immunopathology in Toxicology and Drug Development

View full text Add to dashboard Cite

Macrophages of the sperm granuloma 3 months after vasectomy in the Albino Swiss rat

Cited by 10 publications

References 14 publications

A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota

A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota

Comperative Investigation of Structure of Male Genital System of Ductus Deferens Ligation in Rats

Immunopathology of the Male Reproductive Tract

Contact Info

Product

Resources

About