Macropore tissue ingrowth: a quantitative and qualitative study on hydroxyapatite ceramic

Blitterswijk, Clemens A. van; Grote, J. J.; Kuijpers, W.; Daems, Walter; Groot, K. de

doi:10.1016/0142-9612(86)90071-2

Cited by 191 publications

(61 citation statements)

References 14 publications

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“…However, other values were also found indicating that different calcium salts were present in the membrane. Precipitation of calcium phosphate crystals in the membrane around HA implants may originate from dissolved calcium phosphate from the HA coating, which has been suggested to occur in vivo (van Blitterswijk et al 1986, Beight et al 1989). The fmding could also indicate that the calcium phosphate originated from resorbed, surrounding bone, as the elemental analysis cannot differentiate between calcium phosphate crystals originating from surrounding bone and from dissolved HA.…”

Section: Calcium Phosphate Crystals In Membranementioning

confidence: 99%

Hydroxyapatite coating modifies implant membrane formation

Søballe

Brockstedt-Rasmussen²,

Hansen

et al. 1992

Acta Orthopaedica Scandinavica

178

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Section: Calcium Phosphate Crystals In Membranementioning

confidence: 99%

Hydroxyapatite coating modifies implant membrane formation

Søballe

Brockstedt-Rasmussen²,

Hansen

et al. 1992

Acta Orthopaedica Scandinavica

178

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“…More importantly, incorporating interconnected pores in titanium implants present a promising method to reduce the moduli to the level of natural bones and thus reduce or avoid "stress shielding" and increase longevity of implants. Moreover, the presence of interconnected pores with an appropriate pore size can provide biological anchorage for the surrounding bony tissue via the ingrowth of mineralized tissue into the pore space (van Blitterswijk et al, 1986).…”

Section: Introductionmentioning

confidence: 99%

Ti–6Al–4V triply periodic minimal surface structures for bone implants fabricated via selective laser melting

Yan

Hao

Hussein

et al. 2015

Journal of the Mechanical Behavior of Biomedical Materials

557

236

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Young, Ti-6Al-4V triply periodic minimal surface structures for bone implants fabricated via selective laser melting, Journal of the Mechanical Behavior of Biomedical Materials, http://dx.doi.org/10.1016/j.jmbbm. 2015.06.024 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. C for 4 h, the α' martensite was converted to a mixture of α and β, in which the α phase being the dominant fraction is present as fine laths with the width of 500-800 nm and separated by a small amount of narrow, interphase regions of dark β phase. Also, the microhardness is decreased to 3.71±0.35 GPa due to the coarsening of the microstructure. The 80-95% porosity TPMS lattices exhibit a comparable porosity with trabecular bone, and the modulus is in the range of 0.12-1.25 GPa and thus can be adjusted to the modulus of trabecular bone. At the same range of porosity of 5-10%, the moduli of cortical bone and of the Ti-6Al-4V TPMS lattices are in a similar range. Therefore, the modulus and porosity of Ti-6Al-4V TPMS lattices can be tailored to the levels of human bones and thus reduce or avoid "stress shielding"and increase longevity of implants. Due to the biomorphic designs, and high interconnected porosity and stiffness comparable to human bones, SLM-made Ti-6Al-4V TPMS lattices can be a promising material for load bearing bone implants.

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“…A carbonated form of hydroxyapatite [Ca 10 (PO 4 ) 6 (OH) 2 ] is one of the most abundant materials in mammal bone [1]. It crystallizes within the free space between tropocollagen protein chains ( Fig.…”

Section: Introductionmentioning

confidence: 99%

First-principles study of the biomineral hydroxyapatite

2011

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The biomineral hydroxyapatite Ca 10 (PO 4 ) 6 (OH) 2 is the main mineral constituent of mammal bone. Hydroxyapatite crystallizes in the hexagonal and monoclinic phases, the main difference between them being the orientation of the hydroxyl groups. Using density functional theory we study the energetics of the hexagonal and monoclinic phases along with the several hypothetical crystal structures of hydroxyapatite. The monoclinic phase has the lowest energy, with the hexagonal phase being only 22meV/cell higher in energy. We identify a structural transition path from the hexagonal to monoclinic phase with the activation energy of 0.66 eV per hexagonal cell. At room temperature the transition occurs on a millisecond time scale. The electronic structures of the monoclinic and hexagonal phases are compared. For the hexagonal phase we calculate the phonon frequencies at the Γ-point and elastic constants. Both are in good agreement with available experiment.

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Macropore tissue ingrowth: a quantitative and qualitative study on hydroxyapatite ceramic

Cited by 191 publications

References 14 publications

Hydroxyapatite coating modifies implant membrane formation

Hydroxyapatite coating modifies implant membrane formation

Ti–6Al–4V triply periodic minimal surface structures for bone implants fabricated via selective laser melting

First-principles study of the biomineral hydroxyapatite

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