Macular Choroidal Thickness Measurement by Enhanced Depth Imaging Optical Coherence Tomography in Type (II) Diabetes Mellitus Patients

Abstract

AIM:To evaluate the central (macular) choroidal thickness in diabetic patients with type (II) diabetes mellitus (DM) using enhanced depth imaging optical coherence tomography (EDI-OCT). METHODS: A prospective clinical interventional study included 100 eyes of 100 subjects divided into two groups: Group (A) included 50 eyes of 50 diabetic patients with type (II) DM and Group (B) included 50 eyes of 50 age-matched normal healthy controls with no gender or laterality specification. The central choroidal thickness (CCT) was measured from the posterior edge of RPE to the choroidscleral junction at 1500 µm intervals up to 3000 µm from the fovea using EDI-OCT in 11 quadrants and regions. RESULTS: Mean age in group (A) was 42 ± 7 years (range, 26-50 years), and 39 ± 9 years (range, 25-50 years) in group (B). Mean duration of DM was 7.96 ± 3.9 years in group (A). Subfoveal CCT was 291 ± 42 µm in group (A), (275.31 ± 31 µm for no apparent retinopathy (No DR), 298 ± 42 µm for non-proliferative diabetic retinopathy (NPDR), 309 ± 58 µm for proliferative diabetic retinopathy (PDR), 277 ± 29 µm for diabetic macular edema (DME) absent and 306 ± 47 µm for DME present) while it was 284 ± 54 µm in group (B). There was a statistically significant positive correlation