2021
DOI: 10.4103/joco.joco_150_20
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Macular Infarction Following Intravitreal Clindamycin Injection

Abstract: Purpose: To report a case of Toxoplasma retinochoroiditis that was complicated by macular infarction following intravitreal clindamycin injection. Methods: A 32-year-old otherwise healthy woman with the diagnosis of reactivation of Toxoplasma retinochoroiditis in her right eye, underwent intravitreal clindamycin injection. Shortly after injection, the visual acuity deteriorated, and the fundus examination revealed an… Show more

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Cited by 5 publications
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“…Theoretically, intravitreal route provides a higher drug concentration in the vitreous and can be potentially advantageous, especially in refractory cases [ 23 ]. However, clinicians should not forget that intravitreal clindamycin injection can be fraught with macular infarction [ 24 ]. We preferred to employ a combination of systemic and intravitreal therapy in Case 1 and Case 3, as the clinical picture did not improve enough despite the ongoing systemic antimicrobial treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Theoretically, intravitreal route provides a higher drug concentration in the vitreous and can be potentially advantageous, especially in refractory cases [ 23 ]. However, clinicians should not forget that intravitreal clindamycin injection can be fraught with macular infarction [ 24 ]. We preferred to employ a combination of systemic and intravitreal therapy in Case 1 and Case 3, as the clinical picture did not improve enough despite the ongoing systemic antimicrobial treatment.…”
Section: Discussionmentioning
confidence: 99%