Maculopapular Rash in a Patient With Acquired Immunodeficiency Syndrome

Abstract

A 53-year-old homosexual man was admitted for the second time to the Veterans Administration Hospital, Houston. During his first admission, three months previously, Pneumocystis carinii pneumonia had been diagnosed. The patient was treated with sulfamethoxazole and trimethoprim (Bactrim) (Fig 1). Slight scaling was present over some of the exanthem (Fig 2)

Disseminated cutaneous histoplasmosis in patients infected with human immunodeficiency virus

“…Despite the increase in incidence of disseminated histoplasmosis in endemic and non‐endemic regions, descriptions of the cutaneous histopathologic spectrum that have emanated from these regions are few 6 . Even in single case reports that have documented unusual cutaneous clinical manifestations of disseminated histoplasmosis in the English‐language literature, the histopathological descriptions are short and incomplete 8–19 …”

Fever and Hyperpigmented Papules in an Intravenous Drug Abuser

“…In addition to histologie, microbiologie, and immunocytochemical evidence of infection, sérologie tests, such as complement fixa¬ tion with mycelial or yeast antibody titers or precipitin bands, may be helpful. 13 Intravenous amphotericin B therapy is the treatment of choice at a total dose of at least 35 mg/kg (approximately 2.1 to 2.5 g in a 70-kg individual).3 This dosage is especially important for cure of disseminated histoplasmosis in patients with under¬ lying disease, including those who are immunosuppressive in nature. The experience of Goodwin et al14 in treating 84 individuals with disseminated histo¬ plasmosis with amphotericin B allowed that adults require a total dose of at least 1 g, with 1 to 2 g providing unpredictable but generally favorable results; total dosages of 2 g generally should be curative except for patients with Histoplasma endo¬ carditis, who require an average total dose of 4 g.…”

DISSEMINATED CUTANEOUS HISTOPLASMOSIS IN HIV PATIENT (MIMICKING - MOLLUSCUM CONTAGIOSUM & CRYPTOCOCOSIS )

“…It can be a major cause of morbidity and mortality in these patients. 4 CASE REPORT: A 29yr. old jawan, resident of Delhi, know case of AIDS on ART, presented with productive cough of 4 months duration and multiple papulonodular lesions on face, upper limbs, trunk of 1 month duration to outpatient department of Osmania general hospital, Hyderabad.…”