Madurella mycetomatis-Induced Massive Shoulder Joint Destruction: A Management Challenge

Scolding, Peter; Abbas, Mustafa; Omer, Roa Fathelrahman; Fahal, Ahmed Hassan

doi:10.1371/journal.pntd.0004849

Cited by 7 publications

(4 citation statements)

References 7 publications

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“…Although mycetoma is primarily a localised disease of gradual onset and slow progress, some patients present with massive, aggressive, uncontrolled disease and most of these are fatal. In these patients, the disease progressed wildly and aggressively from the subcutaneous tissue to involve the deep organs such as the urinary bladder, pelvic organs, spinal cord, lung and other structures and resulted in fatal outcome [ 53 , 54 , 55 , 56 ].…”

Section: Aggressive Mycetomamentioning

confidence: 99%

“…In these patients, Madurella mycetomatis had progressed widely without response to the different medical and surgical treatment modalities. Vascular spread, which is a rare phenomenon in mycetoma, may explain the secondary lung lesions encountered in these patients [ 52 , 54 , 55 , 56 ].…”

Section: Aggressive Mycetomamentioning

confidence: 99%

“…In these cases, the urinary bladder, rectum, hip bones and other local structures were involved. The disease was complicated by multiple urinary and rectal fistulae, pathological fractures and all patients died from massive sepsis ( Figure 13 ) [ 52 , 53 , 54 , 55 , 56 ].…”

Section: Aggressive Mycetomamentioning

confidence: 99%

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Mycetoma: The Spectrum of Clinical Presentation

Fahal

Suliman

Hay³

2018

TropicalMed

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Mycetoma is a chronic infection, newly designated by the World Health Organization (WHO) as a neglected tropical disease, which is endemic in tropical and subtropical regions. It follows implantation of infectious organisms, either fungi (eumycetomas) or filamentous bacteria (actinomycetomas) into subcutaneous tissue, from where infection spreads to involve skin, bone and subcutaneous sites, leading to both health related and socioeconomic problems. In common with other NTDs, mycetoma is most often seen in rural areas amongst the poorest of people who have less access to health care. The organisms form small microcolonies that are discharged onto the skin surface via sinus tracts, or that can burrow into other adjacent tissues including bone. This paper describes the clinical features of mycetoma, as early recognition is a key to early diagnosis and the institution of appropriate treatment including surgery. Because these lesions are mostly painless and the majority of infected individuals present late and with advanced disease, simplifying early recognition is an important public health goal.

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Section: Aggressive Mycetomamentioning

confidence: 99%

Section: Aggressive Mycetomamentioning

confidence: 99%

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Mycetoma: The Spectrum of Clinical Presentation

Fahal

Suliman

Hay³

2018

TropicalMed

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“…USG and magnetic resonance imaging (MRI) may allow for non-invasive as well as early diagnosis, thus helping in avoiding complications arising from late diagnosis. [4,5] "dot-in-circle" appearance [Figure 2]. MRI showed round hyperintense nodules in calcaneum with central hypointense dot (dot-in-circle sign) [Figure 3].…”

Section: Introductionmentioning

confidence: 99%

“Dot-in-circle sign:” An ultrasound and magnetic resonance imaging sign for mycetoma

et al. 2022

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Mycetomas are chronic infections of the skin, underlying soft tissues, and sometimes extending up to the bones. They can be actinomycetoma or eumycetoma. Mycetoma is more frequent in tropical and subtropical regions. The definitive diagnosis is made by histopathology and culture in most cases, but these procedures are invasive and time consuming. “Dot-in-circle sign” is an important sign present on both ultrasound (USG) and magnetic resonance imaging (MRI) which imply the presence of distinct hypoechoic lesions surrounding a hyperechoic center. The use of these imaging modalities can help in the early diagnosis and preventing complications. We report two cases of eumycetoma affecting the feet, with characteristic USG and MRI features.

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