MAGIC Syndrome in a Patient With Crohn’s Disease

Naidu, Harini; Szeto, Winnie; Kissin, Eugene Y.; Farraye, Francis A.

doi:10.1093/ibd/izx016

Cited by 4 publications

(2 citation statements)

References 7 publications

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“…A connection of IBD and RPC to date was demonstrated with few case reports [7][8][9][10][11][12][13]. In this case series we report 4 cases of patients who presented with both IBD and RPC.…”

Section: Discussionmentioning

confidence: 70%

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Is Polychondritisa Form of IBD Extraintestinal Manifestation? A Case Series of Patients with Concomitant Relapsing Polychondritis and Inflammatory Bowel Disease

ABG

2022

austinjclincaserep

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Some patients with Inflammatory Bowel Disease (IBD) may experience manifestations in sites other than the gastrointestinal tract. Those Extraintestinal Manifestations (EIMs) may have special treatment projections for those patients. Relapsing Polychondritis (RPC) is a rare auto inflammatory disease that can involve any cartilage tissue of the body, most commonly the cartilages of the ear, nose and eyes but can also affect major airways and the heart. While some cases take more of a benign course with mild to moderate symptoms, some patients will experience devastating debilitating symptoms and even death. Little is known about the pathogenesis of the disease and there are no guidelines for treatment, although immunomodulatory and anti-inflammatory treatment had been described in the literature. In this case series we describe the history of 4 patients with a diagnosis of both RPC and IBD, suggesting a connection between the diseases and the hypothesis that polycondritis is a form of EIM. Acknowledging this may lead to more cases being revealed and to better understanding and more effective treatments.

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Section: Discussionmentioning

confidence: 70%

“…A connection between RPS and IBD has been described in few case studies of patients with UC [7][8][9][10] and CD [11][12][13]. Here we describe 4 patients exhibiting both IBD and RPC.…”

Section: Introductionmentioning

confidence: 75%