Magnesium and strontium doped octacalcium phosphate thin films by matrix assisted pulsed laser evaporation

Boanini, Elisa; Torricelli, Paola; Fini, Milena; Sima, Félix; Serban, N.; Mihăilescu, I. N.; Bigi, Adriana

doi:10.1016/j.jinorgbio.2011.11.003

Cited by 74 publications

(59 citation statements)

References 41 publications

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“…This remark is sustained by the presence of the strong low angle relection 2θ of 4.7° and the series of relections in the range of 30-34°. Comparing these results with the previous one related to OCP deposition by PLD [70], one can remark that the gentle deposition conditions of M"PLE ofer a higher degree of OCP crystallinity with respect to PLD [31]. The homogeneous distribution of magnesium and strontium on the thin ilm surface was evidenced by EDS analysis (Figure ).…”

Section: Study Of Thin Ilm Growth Mechanisms By Laser Ablationsupporting

confidence: 74%

“…"oanini et al evaluate the possibility to deposit thin ilms of magnesium substituted OCP (Mg:OCP) and strontium substituted OCP (Sr:OCP) on Ti substrates [31].…”

Section: Octacalcium Phosphatementioning

confidence: 99%

“…Some interesting results were obtained by laser ablation of Mg:OCP and Sr:OCP compounds using the M"PLE technique [31]. The X-ray Difraction (XRD) paterns revealed that all M"PLE coatings are constituted of OCP.…”

Section: Study Of Thin Ilm Growth Mechanisms By Laser Ablationmentioning

confidence: 99%

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Laser Ablation of Biomaterials

Popescu-Pelin¹,

Ristoscu²,

Mihăilescu³

2016

Applications of Laser Ablation - Thin Film Deposition, Nanomaterial Synthesis and Surface Modification

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Abstract"iomaterials, deined by high biocompatibility and biodegradability, are intensively used in medical applications, mainly to replace partial or total, damaged or destroyed hard or soft tissues. Most of them are used not only as coatings for implant coverage but also as parts for some medical devices. In the last decades, researchers sought to ind the optimum processing methods and parameters to modify or deposit the biomaterial of interest. "n important family of techniques, used to process a biomaterial, is represented by laser techniques, based upon laser ablation phenomenon. Laser ablation of biomaterials ensures the transference or modiication with good precision and without or with minimal disruptions generated. To obtain thin coatings from biomaterials, one can use deposition techniques: pulsed laser deposition (PLD) or matrix-assisted pulsed laser evaporation (M"PLE). These techniques are chosen according to the selected biomaterial and desired performances of the obtained coating. Therefore, some sensitive biomaterials can be transferred only by M"PLE. Some results in the ield of calcium phosphates deposited by PLD or M"PLE are presented, proving the usefulness of these biomaterials for medical applications.

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Section: Study Of Thin Ilm Growth Mechanisms By Laser Ablationsupporting

confidence: 74%

“…"oanini et al evaluate the possibility to deposit thin ilms of magnesium substituted OCP (Mg:OCP) and strontium substituted OCP (Sr:OCP) on Ti substrates [31].…”

Section: Octacalcium Phosphatementioning

confidence: 99%

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Laser Ablation of Biomaterials

Popescu-Pelin¹,

Ristoscu²,

Mihăilescu³

2016

Applications of Laser Ablation - Thin Film Deposition, Nanomaterial Synthesis and Surface Modification

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“…74 Octacalcium phosphate (OCP) is a promising alternative to hydroxyapatite as biomaterial for hard tissue repair. OCP, Mg- SrOCP coated surfaces comparing to OCT coated surfaces 75 [ Fig. 4(b)].…”

Section: Biomaterials Deposition Using Matrix Assisted Pulsed Lasementioning

confidence: 99%

Laser-assisted biofabrication in tissue engineering and regenerative medicine

et al. 2016

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Controlling the spatial arrangement of biomaterials and living cells provides the foundation for fabricating complex biological systems. Such level of spatial resolution (less than 10 lm) is difficult to be obtained through conventional cell processing techniques, which lack the precision, reproducibility, automation, and speed required for the rapid fabrication of engineered tissue constructs. Recently, laserassisted biofabrication techniques are being intensively developed with the use of computer-aided processes for patterning and assembling both living and nonliving materials with prescribed 2D or 3D organization. In this review, we discuss laser-assisted fabrication methods, including laser tweezers, multi-photon polymerization, laser-induced forward transfer (LIFT), matrix assisted pulsed laser evaporation (MAPLE), and laser ablation as well as their applications in biological science and biomedical engineering. These advanced technologies enable the precise manipulation of in vitro cellular microenvironments and the ability to engineer functional tissue constructs with high complexity and heterogeneity, which serve in regenerative medicine, pharmacology, and basic cell biology studies.

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“…By optimization of the MAPLE deposition parameters (laser wavelength, repetition rate, laser fluence, solvent type, solute concentration, substrate temperature, background gas and pressure), the process can proceed without significant material decomposition [6,25,81]. It was demonstrated that MAPLE could provide more crystalline layers as compared to PLD method from the same materials [87]. Recent comprehensive reviews on MAPLE deposition of organic, biological and nanoparticle thin films illustrated large potential (drug delivery, biosensors, etc.)…”

Section: Matrix-assisted Pulsed Laser Evaporation (Maple)mentioning

confidence: 99%

Biopolymer Thin Films Synthesized by Advanced Pulsed Laser Techniques

Axente¹,

Sima²,

Ristoscu³

et al. 2016

Recent Advances in Biopolymers

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This chapter provides an overview of recent advances in the field of laser-based synthesis of biopolymer thin films for biomedical applications. The introduction addresses the importance of biopolymer thin films with respect to several applications like tissue engineering, cell instructive environments, and drug delivery systems. The next section is devoted to applications of the fabrication of organic and hybrid organic-inorganic coatings. Matrix-assisted pulsed laser evaporation (MAPLE) and Combinatorial-MAPLE are introduced and compared with other conventional methods of thin films assembling on solid substrates. Advantages and limitations of the methods are pointed out by focusing on the delicate transfer of bio-macromolecules, preservation of properties and on the prospect of combinatorial libraries' synthesis in a single-step process. The following section provides a brief description of fundamental processes involved in the molecular transfer of delicate materials by MAPLE. Then, the chapter focuses on the laser synthesis of two polysaccharide thin films, namely Dextran doped with iron oxide nanoparticles and Levan, followed by an overview on the MAPLE synthesis of other biopolymers. The chapter ends with summary and perspectives of this fast-expanding research field, and a rich bibliographic database.

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Magnesium and strontium doped octacalcium phosphate thin films by matrix assisted pulsed laser evaporation

Cited by 74 publications

References 41 publications

Laser Ablation of Biomaterials

Laser Ablation of Biomaterials

Laser-assisted biofabrication in tissue engineering and regenerative medicine

Biopolymer Thin Films Synthesized by Advanced Pulsed Laser Techniques

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