Magnesium and zinc levels in obese women with PCOS

Abstract

The study focused on magnesium and zinc and their relationship with insulin resistance in women with Polycystic Ovarian Syndrome (PCOS), where 61 samples were taken from women who had the syndrome and 45 samples from women who weren't affected by the syndrome as a control group. The results showed that there is a significant negative correlation between magnesium and zinc with insulin resistance (IR) at (p = 0.001) and ( p = 0.004) respectively, for those with the syndrome, due to the high levels of insulin in their blood and the incapacity of zinc and magnesium to play their respective roles in regulating the insulin and blood sugar level. Their relationship with body mass index (BMI) were strongly significant at (p = 0.009) and (p = 0.01) respectively, and with waist-hip ratio (WHR) were significant at (p = 0.002) and (p = 0.001) respectively. Finally, the study proved that magnesium and zinc are two new markers of increased risk factors for PCOS in women with insulin resistance.

Efecto del fármaco metformina sobre los niveles de zinc y magnesio en mujeres con síndrome de ovario poliquístico

“…enero-junio 2024 Gac Med Bol 2024; 47(1): Some researchers try to find the effect of metformin on magnesium and zinc in type II diabetes patients [21][22][23] , in chronic kidney disease 24 , before and after surgery 25 and one research tries to find the effect of metformin on zinc and magnesium level23 Other type of research try to find the effect of zinc and magnesium as an added complement to metformin treatment [26][27][28][29] . The third type of research tries to determine the level of magnesium and zinc in polycystic ovary syndrome 12,16,30 .…”