Magnesium ion is beneficial in hypothermic crystalloid cardioplegia

Early postoperative arrhythmias after pediatric cardiac surgery

“…This effect is likely how magnesium improves ventricular recovery in hypothermic cardioplegia solutions when coupled with a low calcium level. 18,19 The advantages of del Nido cardioplegia have been described in pediatric as well as adult patients. 20 The limitations of this study include the fact that the study population may have been too small to gain any major insight into risk factors because the incidence of all arrhythmias was low; even JET was extremely low, barely 3.5%, which was totally unexpected.…”

“…This effect is likely how magnesium improves ventricular recovery in hypothermic cardioplegia solutions when coupled with a low calcium level. 18,19 The advantages of del Nido cardioplegia have been described in pediatric as well as adult patients. 20…”

Arrhythmias in Children in Early Postoperative Period After Cardiac Surgery

“…23 It is known that magnesium improves ventricular recovery after hypothermic cardioplegic arrest. 24,25 A normal to high magnesium blood level prevents intracellular calcium accumulation, thereby reducing arrhythmias. 23 Some believe that inclusion of mannitol (as a free radical scavenger) in cardioplegia solution may reduce arrhythmias.…”

Del Nido cardioplegia – what is the current evidence?

“…Magnesium additive blocks the calcium channels [ 10 ], which has proved to improve myocardial recovery [ 11 , 12 ].…”