Magnetic- and pH-responsive κ-carrageenan/chitosan complexes for controlled release of methotrexate anticancer drug

Mahdavinia, Gholam Reza; Mosallanezhad, Amirabbas; Soleymani, Moslem; Sabzi, Mohammad

doi:10.1016/j.ijbiomac.2017.01.012

Cited by 115 publications

(44 citation statements)

References 45 publications

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“…Several natural polymers like starch, cellulose, chitosan, cyclodextrin, alginate and Carrageenan have been used as protective shell for the synthesis of magnetic nanoparticles with considerable stability and controlled size. Also, a protective shell can be used for modification with specific ingredients, such as different drugs, particular binding sites, catalytic active components, or other functional groups.…”

Section: Introductionmentioning

confidence: 99%

Magnetic Bisphosphonic Acid Nanohybrid Catalyzed Heterogeneous Synthesis of Heterocylcles

2018

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A novel inorganic-organic hybrid nanocomposite (PBA@SMNP) was synthesized by functionalization of starch-coated iron oxide nanoparticles with bisposphonic acid. The particles were characterized by XRD, FT-IR, TEM, SEM, EDS, TGA and VSM. TEM images demonstrate a quasispherical particle shape for the assynthesized nanocomposite with an average diameter of 11 nm. The phosphonic acid functionalized nanoparticles catalysed the synthesis of quinoxaline and benzimidazole derivatives in ethanol. This catalytic system has an extensive substrate domain, and is eco-friendly and cost effective. The heterogeneity of system with simple work-up procedure that uses a green solvent are the advantages of the present high yielding protocol. More importantly, the catalyst is readily removed from the reaction medium with an external magnet and can be retrieved several times without any loss of efficiency.

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Section: Introductionmentioning

confidence: 99%

Magnetic Bisphosphonic Acid Nanohybrid Catalyzed Heterogeneous Synthesis of Heterocylcles

2018

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“…The magnetic properties of magnetic hydrogels depend to a large extent on the type of magnetic particles, the particle size, 28 and the content. 29 Magnetic nanoparticles also have the ability to bind to the cell surface, and the response of magnetic particles under the inuence of external magnetic elds makes it possible to inuence cell differentiation and proliferation. [30][31][32] But we think that the benet effect of magnetic stem cell phenotype needs further external stimulation.…”

Section: Discussionmentioning

confidence: 99%

Pulse electromagnetic fields enhance the repair of rabbit articular cartilage defects with magnetic nano-hydrogel

et al. 2020

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“…Beyond technological applications mentioned in this session, hydrogel and nanocomposites based on CS and their derivatives have been studied for other several applications, such as contact lenses [238,239], enzyme and cell separations and immobilizations [71,[240][241][242][243], DNA delivering [244], cartilage and skin regenerations [245][246][247][248][249], biosensors [250][251][252], submucosal fluid or injections [253][254][255][256][257], tissue engineering [258][259][260][261][262][263], postoperative adhesion prevention [264][265][266], cancer treatment [267][268][269][270], orthopedic applications [271,272], artificial muscles [273], and others. Important characteristics of some cited applications are discussed as follows.…”

Section: Other Technological Applicationsmentioning

confidence: 99%

Hydrogels Based on Chitosan and Chitosan Derivatives for Biomedical Applications

Rufato¹,

Galdino²,

Ody³

et al. 2019

Hydrogels - Smart Materials for Biomedical Applications

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Chitosan (CS) is a polymer obtained from chitin, being this, after the cellulose, the most abundant polysaccharide. The fact of (i) CS being obtained from renewable sources; (ii) CS to possess capability for doing interactions with different moieties being such capability dependent of pH; (iii) plenty of possibilities for chemical modification of CS; and (iv) tuning the final properties of CS derivatives makes this polymer very interesting in academic and technological points of view. In this way, hydrogels based on CS and on CS derivatives have been widely used for biomedical applications. Other important technological applications can be also cited, such as adsorbent of metals and dyes in wastewater from industrial effluents. In pharmaceutical field, hydrogels based on CS are often used as drugs' and proteins' carrier formulations due to the inherent characteristics such as the biocompatibility, nontoxicity, hydrophilicity, etc. This chapter is an attempt for updating and joining the plenty of available information regarding the preparation, characterization, and biomedical application of hydrogels based on chitosan and chitosan derivatives. More than 260 references are provided, being the majority of them published in the last 10 years.

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Magnetic- and pH-responsive κ-carrageenan/chitosan complexes for controlled release of methotrexate anticancer drug

Cited by 115 publications

References 45 publications

Magnetic Bisphosphonic Acid Nanohybrid Catalyzed Heterogeneous Synthesis of Heterocylcles

Magnetic Bisphosphonic Acid Nanohybrid Catalyzed Heterogeneous Synthesis of Heterocylcles

Pulse electromagnetic fields enhance the repair of rabbit articular cartilage defects with magnetic nano-hydrogel

Hydrogels Based on Chitosan and Chitosan Derivatives for Biomedical Applications

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